Home / Current Issue / Paper 1701070
Compounds From Turraea Abyssinica
Subject area: Physical Sciences and Environment · Area of research: Chemistry
Abstract
Turraea abyssinica belong to the Turraea genus of the Meliaceae family and is used by the Samburus of Kenya as rungus, firewood and as fruits to induce vomiting. No phytochemicals have been reported on the Narok Kenya species. The leaves were collected from Narok Kenya, identified and voucher specimen kept for reference in Biological Department, Egerton University, Kenya. Dry powder of stem bark was successively extracted with hexane, dichloromethane, ethyl acetate and methanol for seventy two hours. The solvents were evaporated under reduced pressure using a rotary evaporator (B?chi type R-205). With repeated column chromatography using a solvent step gradient of 20% methanol in dichloromethane, 47.5% and 95% dichloromethane in diethylether, three compounds, β-Sitosterol(1), Scopoletein(2) and 2-(1,2-Dihydroxypropyl)tetradecanoic acid (3) were isolated. Identification of pure compounds was achieved by 1H and 13C NMR (500 MHz) spectroscopy.
Keywords
Compounds, Narok, stembark, Turraea abyssinica
References
[1] A.Z. Muhammad, U.K. Saadat, U.R. Taj, and S.S.S. Muhammad (2017). β-sitosterol and stigmasterol from the roots of Indigofera heterantha. Pharmacy & Pharmacology International Journal 5: 203-207.
[2] Biological Magnetic Resonance Data Bank. .A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules.
[3] Chaturvedula and Prakash (2012). Isolation of Stigmasterol and β-Sitosterol from the dichloromethane extract of Rubus suavissimus,International Current Pharmaceutical Journal 9: 239-242
[4] C. Leonardo, S. de C. Rosabel, M. Eduardo and S.C. Jose (2002). Oleanane Triterpenoids from Cedrela montana (Meliaceae). Z. Naturforsch 57:575-578.
[5] D. Akhmad, K. Soleh, B.S.K. Leonardus and M.S. Yana, M (2012). Scopoletin, a coumarin derivative compound isolated from Macaranga gigantifolia Merr. Applied Pharmaceutical Science 2: 175-177.
[6] E.B. Omoruyi, A.J. Afolayan and G. Bradley (2014). Chemical composition profiling and antifungal activity of the Essential oil and plant extracts of Mesembryanthemum edule (L) bolus leaves. Traditional Comlementary and Alternative Medicines 11: 19-30.
[7] J. Zhou, L.Wang, L. Wei, Y. Zheng, H. Zhang, Y. Wang, P.Cao, A. Niu, J. Wang and Y. Dai (2012). Synthesis and Antitumor Activity of Scopoletin derivertives. Letters in Drug Design & Discovery 9: 397-401.
[8] M.W. Ndung’u (2002). Isolation and characterization of anti-mosquito compounds from selected East African meliaceae plants. PhD Thesis.Jomo Kenyatta University of Agriculture and Technology, Kenya.
[9] P.J. Facchini, K.L. Huber-Allanach and L.W. Tari (2000). Plant aromatic l-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications. Phytochemistry 54: 21-138.
[10] R. Amit and S. Shailendra (2006). Limonoids: Overview of significant Bioactive Triterpenes Distributed in Plant Kingdom. Biolgical Pharmaceutical Bulletin 29: 191-201.
[11] S. Soodabeh, M. Azadeh, R.G. Ahmad and A. Mohammad (2014). The story of Beta Sitosterol-A review. European Journal of Medicinal Plants 4: 590-609.
How to cite this paper
@article{1701070,
author = {Kinuthia Esther Wanjiru, Mwangi Elizabeth Muthoni, Cheplogoi Peter Kiplagat},
title = {Compounds From Turraea Abyssinica},
journal = {Iconic Research And Engineering Journals},
year = {2019},
volume = {2},
number = {10},
pages = {32-36},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1701070.pdf},
abstract = {Turraea abyssinica belong to the Turraea genus of the Meliaceae family and is used by the Samburus of Kenya as rungus, firewood and as fruits to induce vomiting. No phytochemicals have been reported on the Narok Kenya species. The leaves were collected from Narok Kenya, identified and voucher specimen kept for reference in Biological Department, Egerton University, Kenya. Dry powder of stem bark was successively extracted with hexane, dichloromethane, ethyl acetate and methanol for seventy two hours. The solvents were evaporated under reduced pressure using a rotary evaporator (B?chi type R-205). With repeated column chromatography using a solvent step gradient of 20% methanol in dichloromethane, 47.5% and 95% dichloromethane in diethylether, three compounds, β-Sitosterol(1), Scopoletein(2) and 2-(1,2-Dihydroxypropyl)tetradecanoic acid (3) were isolated. Identification of pure compounds was achieved by 1H and 13C NMR (500 MHz) spectroscopy.},
keywords = {Compounds, Narok, stembark, Turraea abyssinica},
month = {April},
}