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Statistical Analysis On The Efficacy Of Cutting-Edge Technology (Truscan) Compared To Gold Standard (Hplc) In Detecting Counterfeit Medicines In Nigeria.
Subject area: Science,Engineering and Technology · Area of research: Science (Statistics)
Abstract
Cutting-edge technologies are new innovation introduced into regulatory industries or organisations to ease operations. In this thesis, therefore examines the efficiency of TruScan to determine the counterfeited medicines compare to HPLC which is the gold standard. More so, to assess the correlation between the results obtained using TruScan? (Raman spectrometer) and those from the HPLC. It was realised at the end of the analysis that, TruScan has 88% efficient compare to HPL which is the gold standard could do. Also the device has the ability of 89% to detect that the product has passed when indeed it passed; again, it has 85% confirmatory that the drugs failed the Test when HPLC has already stated (see R-Language software results obtained in Chapter Four). In kappa agreement, the analysis shows that the device has 62% substantial agreement or correlation between HPLC. McNemar?s analysis also shows that there exists a relationship between TruScan and HPLC which is the gold standard.
Keywords
Cutting-edge, Efficacy, Medicine, TruScan
References
[1] W.H.O (2011) Definition of Counterfeiting of Drugs. Report
[2] J. H. Knox, et al. (1978). “High-Performance Liquid Chromatography”. Published by Edinburgh university press. Source: https://www.cabdirect.org/cabdirect/abstract
[3] Orhii (2011). “Fighting Counterfeiting of Medicines: Efforts at Safeguarding Public Health in Nigeria”. Published by In Him ResourcesLtd 21, Abiodun Wright Avenue, Ikate, Surelere Lagos Nigeria.
[4] ThermoScientific.com (2014). “Probabilistic Approach for Material Verification and Identification in Pharmaceutical Applications”.[online] available at: https://www.thermofisher.com
[5] Scientific, Thermofisher.com (2016). “Handheld Raman Instrument for pharmaceutical raw material inspection: from the lab to the loading dock”. Available at https://www.pharmaceuticalonline.com
[6] A.J. Kerlinger (1999). “Sensitivity, Specificity, and Predictive Values: Foundations, Pliabilities, and Pitfalls in Research and Practice”. Available at https://www. Performance Liquid Chromatography (HPLC): Principle, Types, Instrumentation and Applications. Available at https://www.laboratoryinfo.com/hplc/ Oxford Advanced Learner’s Dictionary 6 th Edition, Oxford University press. TruScan RM Analyzer for Material Testing. Available at: https://www.thermofisher.com/TRUSCANRM LABORATORY RESULTS TRUSCAN RESULTS Passed Failed Total Passed 1863 57 1920 Failed 236 322 558 Total 2099 379 2478
How to cite this paper
@article{1701970,
author = {Olanrewaju S. O., Temanenge F. U},
title = {Statistical Analysis On The Efficacy Of Cutting-Edge Technology (Truscan) Compared To Gold Standard (Hplc) In Detecting Counterfeit Medicines In Nigeria.},
journal = {Iconic Research And Engineering Journals},
year = {2020},
volume = {3},
number = {9},
pages = {6-14},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1701970.pdf},
abstract = {Cutting-edge technologies are new innovation introduced into regulatory industries or organisations to ease operations. In this thesis, therefore examines the efficiency of TruScan to determine the counterfeited medicines compare to HPLC which is the gold standard. More so, to assess the correlation between the results obtained using TruScan? (Raman spectrometer) and those from the HPLC. It was realised at the end of the analysis that, TruScan has 88% efficient compare to HPL which is the gold standard could do. Also the device has the ability of 89% to detect that the product has passed when indeed it passed; again, it has 85% confirmatory that the drugs failed the Test when HPLC has already stated (see R-Language software results obtained in Chapter Four). In kappa agreement, the analysis shows that the device has 62% substantial agreement or correlation between HPLC. McNemar?s analysis also shows that there exists a relationship between TruScan and HPLC which is the gold standard.},
keywords = {Cutting-edge, Efficacy, Medicine, TruScan},
month = {March},
}