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Synthesis and Antibacterial Activities of 2-amino-N-(p-Chlorophenyl) acetamide derivatives
Subject area: Biological & Medical Sciences · Area of research: Medical Sciences
Abstract
As eries of 2-amino-N-(p-Chlorophenyl) acetamide derivatives (5a ~ 5d) were synthesized by the reaction of 2-bromo-N-(p-Chlorophenyl) acetamide (3) with various amine (4a ~ 4d) at room temperature. The antibacterial activities of all the compounds were evaluated againstfour bacterial strains(Acinetobacter baumannii, Pseudomonas aeruginosa andStaphylococcus aureus)and showed moderate to high activities.
Keywords
N-phenylacetamide, Antibacterial Activity, Synthesis.
References
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How to cite this paper
@article{1702353,
author = {Yuh-Wern Wu, Jyh-Ferng Yang, Li-Yeh Chuang, Jian-Fong Huang},
title = {Synthesis and Antibacterial Activities of 2-amino-N-(p-Chlorophenyl) acetamide derivatives},
journal = {Iconic Research And Engineering Journals},
year = {2020},
volume = {3},
number = {12},
pages = {144-147},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1702353.pdf},
abstract = {As eries of 2-amino-N-(p-Chlorophenyl) acetamide derivatives (5a ~ 5d) were synthesized by the reaction of 2-bromo-N-(p-Chlorophenyl) acetamide (3) with various amine (4a ~ 4d) at room temperature. The antibacterial activities of all the compounds were evaluated againstfour bacterial strains(Acinetobacter baumannii, Pseudomonas aeruginosa andStaphylococcus aureus)and showed moderate to high activities.},
keywords = {N-phenylacetamide, Antibacterial Activity, Synthesis.},
month = {June},
}