International Peer-Reviewed JournalOpen AccessISSN 2456-8880
irejournals@gmail.com+91-7433024337

Home / Current Issue / Paper 1702645

1702645 Vol 4 · Issue 9 Download Paper

Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis

Gaurav Pandey Vinay Kumar Varshney Mandeep Kumar Tanmay Singh Abhinav Rawat

Subject area: Physical Sciences and Environment  ·  Area of research: Moringa oleifera Lam.

Abstract

Moringa oleifera commonly called ?Sehjan? in India, is?one of the most cultivated and distributed plant species in the region. It?is a variable species that typically grows to 10 meters in height and has multiple uses as a vegetable, spice, medicinal plant and supply of culinary and cosmetic oil. All the parts of?plant have a range of vital nutrients and thus provide rich minerals, proteins, vitamins, ? -carotene, amino acids, and various phenolic contents. Moringa has been found to be of tremendous help?in fighting malnutrition especially in children and nursing mothers because of its high nutrition and vitamin density. More?importantly, its leaves can have nearly four times more either vitamin A, calcium, iron, vitamin C and potassium contents compared with well-known sources like carrots, milk, spinach, oranges and banana. In addition,?the protein quality in Moringa leaves is better than milk and eggs. This review provides an extensive discussion?on the phytochemicals, bioactivities, medicinal values, and nutritional value of M. oleifera.

Keywords

Moringa oleifera, Phytochemicals, Nutritional value, Glucosinolate, ?-Carotene

References

[1] S. Mishra, S. Lakhawat, and H. Pandey, "Moringa oleifera: A Miracle Plant," Popular Kheti, vol. 8, no. 2, pp. 29–30, 2020.

[2] S.-Y. Pan, S.-F. Zhou, S.-H. Gao et al., “New perspectives on how to discover drugs from herbal medicines: CAM’s outstanding contribution to modern therapeutics,” Evid. Based Complement. Alternat. Med., vol. 2013, Article ID 627375, 2013, doi: 10.1155/2013/627375.

[3] C. N. Kunyanga, J. K. Imungi, and V. Vellingiri, “Nutritional evaluation of indigenous foods with potential food-based solution to alleviate hunger and malnutrition in Kenya,” J. Appl. Biosci., vol. 67, pp. 5277–5288, 2013, doi: 10.4314/jab.v67i0.95049.

[4] B. Padayachee and H. Baijnath, “An overview of the medicinal importance of Moringaceae,” J. Med. Plants Res., vol. 6, pp. 5831–5839, 2012.

[5] R. K. Saini, “Studies on enhancement of carotenoids, folic acid, iron and their bioavailability in M. oleifera and in vitro propagation,” Ph.D. dissertation, Univ. of Mysore, India, 2015.

[6] G. C. Stevens, K. P. Baiyeri, and O. Akinnnagbe, “Ethno-medicinal and culinary uses of M. oleifera Lam. in Nigeria,” J. Med. Plants Res., vol. 7, pp. 799–804, 2013.

[7] R. K. Saini, P. Manoj, N. P. Shetty et al., “Dietary iron supplements and M. oleifera leaves influence the liver hepcidin messenger RNA expression and biochemical indices of iron status in rats,” Nutr. Res., vol. 34, pp. 630–638, 2014, doi: 10.1016/j.nutres.2014.07.003.

[8] R. K. Saini, K. V. H. Prashanth, N. P. Shetty, and P. Giridhar, “Elicitors, SA and MJ enhance carotenoids and tocopherol biosynthesis and expression of antioxidant related genes in M. oleifera Lam. leaves,” Acta Physiol. Plant., vol. 36, pp. 2695–2704, 2014, doi: 10.1007/s11738014-1640-7.

[9] R. K. Saini, N. P. Shetty, and P. Giridhar, “Carotenoid content in vegetative and reproductive parts of commercially grown M. oleifera Lam. cultivars from India by LC–MS,” Eur. Food Res. Technol., vol. 238, pp. 971–978, 2014.

[10] R. K. Saini, N. P. Shetty, and P. Giridhar, “GC-FID/MS analysis of fatty acids in Indian cultivars of M. oleifera: potential sources of PUFA,” J. Am. Oil Chem. Soc., vol. 91, pp. 1029–1034, 2014.

[11] M. M. Azam, A. Waris, and N. M. Nahar, “Prospects and potential of fatty acid methyl esters of some non-traditional seed oils for use as biodiesel in India,” Biomass Bioenergy, vol. 29, pp. 293–302, 2005.

[12] U. Rashid, F. Anwar, B. R. Moser, and G. Knothe, “Moringa oleifera oil: a possible source of biodiesel,” Bioresour. Technol., vol. 99, pp. 8175–8179, 2008, doi: 10.1016/j.biortech.2008.03.066.

[13] M. Mofijur et al., “Comparative evaluation of performance and emission characteristics of Moringa oleifera and Palm oil based biodiesel in a diesel engine,” Ind. Crops Prod., vol. 53, pp. 78–84, 2014, doi: 10.1016/j.indcrop.2013.12.011.

[14] S. K. Kansal and A. Kumari, “Potential of M. oleifera for the treatment of water and wastewater,” Chem. Rev., vol. 114, pp. 4993–5010, 2014, doi: 10.1021/cr400093w.

[15] P. Upadhyay et al., “Moringa oleifera: A review of the medical evidence for its nutritional and pharmacological properties,” Int. J. Res. Pharm. Sci., vol. 5, no. 2, pp. 12–16, 2015.

[16] J. Pullen and K. Saeed, “Experimental study of the factors affecting the oxidation stability of biodiesel FAME fuels,” Fuel Process Technol., vol. 125, pp. 223–235, 2014.

[17] A. Leone et al., “Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of M. oleifera leaves: an overview,” Int. J. Mol. Sci., vol. 16, pp. 12791–12835, 2015, doi: 10.3390/ijms160612791.

[18] R. K. Saini, N. P. Shetty, M. Prakash, and P. Giridhar, “Effect of dehydration methods on retention of carotenoids, tocopherols, ascorbic acid and antioxidant activity in M. oleifera leaves and preparation of a RTE product,” J. Food Sci. Technol., vol. 51, pp. 2176–2182, 2014.

[19] F. Anwar, S. Latif, M. Ashraf, and A. H. Gilani, “Moringa oleifera: a food plant with multiple medicinal uses,” Phytother. Res., vol. 21, pp. 17–25, 2007, doi: 10.1002/ptr.2023.

[20] J. P. Coppin et al., “Determination of flavonoids by LC/MS and anti-inflammatory activity in Moringa oleifera,” J. Funct. Foods, vol. 5, pp. 1892–1899, 2013.

[21] W. Nouman et al., “Profiling of polyphenolics, nutrients and antioxidant potential of germplasm’s leaves from seven cultivars of Moringa oleifera Lam.,” Ind. Crops Prod., vol. 83, pp. 166–176, 2016, doi: 10.1016/j.indcrop.2015.12.032.

[22] R. K. Saini et al., “Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model,” J. Food Sci. Technol., vol. 53, pp. 511–520, 2016, doi: 10.1007/s13197-015-1828-x.

[23] M. Scotti et al., “Modeling cellular compartmentation in one-carbon metabolism,” Wiley Interdiscip. Rev. Syst. Biol. Med., vol. 5, pp. 343–365, 2013, doi: 10.1002/wsbm.1209.

[24] J. Williams et al., “Updated estimates of neural tube defects prevented by mandatory folic acid fortification—United States, 1995–2011,” MMWR Morb. Mortal. Wkly. Rep., vol. 64, pp. 1–5, 2015.

[25] D. I. Sánchez-Machado et al., “Effect of the refining process on Moringa oleifera seed oil quality,” Food Chem., vol. 187, pp. 53–57, 2015, doi: 10.1016/j.foodchem.2015.04.031.

[26] P. R. Bhutada et al., “Solvent-assisted extraction of oil from Moringa oleifera Lam. seeds,” Ind. Crops Prod., vol. 82, pp. 74–80, 2016, doi: 10.1016/j.indcrop.2015.12.004.

[27] B. S. Ogunsina, C. Radha, and R. S. Govardhan Singh, “Physicochemical and functional properties of full-fat and defatted M. oleifera kernel flour,” Int. J. Food Sci. Technol., vol. 45, pp. 2433–2439, 2010, doi: 10.1111/j.1365-2621.2010.02423.x.

[28] E. M. B. Teixeira et al., “Chemical characteristics and fractionation of proteins from M. oleifera Lam. leaves,” Food Chem., vol. 147, pp. 51–54, 2014, doi: 10.1016/j.foodchem.2013.09.135.

[29] A. T. Oyeyinka and S. A. Oyeyinka, “Moringa oleifera as a food fortificant: recent trends and prospects,” J. Saudi Soc. Agric. Sci., 2016, doi: 10.1016/j.jssas.2016.02.002.

[30] F. Farooq et al., “Medicinal properties of Moringa oleifera: an overview of promising healer,” J. Med. Plants Res., vol. 6, pp. 4368–4374, 2012.

[31] M. Mbikay, “Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review,” Front. Pharmacol., vol. 3, p. 24, 2012, doi: 10.3389/fphar.2012.00024.

[32] S. J. Stohs and M. J. Hartman, “Review of the safety and efficacy of Moringa oleifera,” Phytother. Res., vol. 29, pp. 796–804, 2015, doi: 10.1002/ptr.5325.

[33] S. Sreelatha, A. Jeyachitra, and P. R. Padma, “Antiproliferation and induction of apoptosis by Moringa oleifera leaf extract on human cancer cells,” Food Chem. Toxicol., vol. 49, pp. 1270–1275, 2011.

[34] V. A. Giridhari, D. Malathi, and K. Geetha, “Antidiabetic property of drumstick (Moringa oleifera) leaf tablets,” Int. J. Health Nutr., vol. 2, pp. 1–5, 2011.

[35] P. G. Jain et al., “Hypolipidemic activity of Moringa oleifera Lam., Moringaceae, on high fat diet induced hyperlipidemia in albino rats,” Rev. Bras. Farmacogn., vol. 20, pp. 969–973, 2010, doi: 10.1590/S0102-695X2010005000038.

[36] V. S. Nambiar, P. Guin, S. Parnami, and M. Daniel, “Impact of antioxidants from drumstick leaves on the lipid profile of hyperlipidemics,” J. Herb. Med. Toxicol., vol. 4, pp. 165–172, 2010.

[37] L. Berkovich et al., “Moringa oleifera aqueous leaf extract down-regulates nuclear factor-kappaB and increases cytotoxic effect of chemotherapy in pancreatic cancer cells,” BMC Complement. Altern. Med., vol. 13, p. 212, 2013.

[38] W. J. Fahey, “Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic and prophylactic properties. Part 1,” Trees for Life J., vol. 1, p. 5, 2005.

How to cite this paper

Gaurav Pandey, Vinay Kumar Varshney, Mandeep Kumar, Tanmay Singh, Abhinav Rawat "Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis" Iconic Research And Engineering Journals Volume 4 Issue 9 2021 Page 287-294
Gaurav Pandey, Vinay Kumar Varshney, Mandeep Kumar, Tanmay Singh, Abhinav Rawat "Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis" Iconic Research And Engineering Journals, vol. 4, no. 9, Mar. 2021
Gaurav Pandey, Vinay Kumar Varshney, Mandeep Kumar, Tanmay Singh, Abhinav Rawat (2021). Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis. Iconic Research And Engineering Journals, 4(9).
Gaurav Pandey, Vinay Kumar Varshney, Mandeep Kumar, Tanmay Singh, Abhinav Rawat "Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis" Iconic Research And Engineering Journals, vol. 4, no. 9, Mar. 2021.
@article{1702645,
      author = {Gaurav Pandey, Vinay Kumar Varshney, Mandeep Kumar, Tanmay Singh, Abhinav Rawat},
      title = {Integrative Review on the Bioactive Composition, Nutritional Efficacy, and Multifunctional Applications of Moringa oleifera Lam.: A Phytochemical and Therapeutic Synopsis},
      journal = {Iconic Research And Engineering Journals},
      year = {2021},
      volume = {4},
      number = {9},
      pages = {287-294},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1702645.pdf},
      abstract = {Moringa oleifera commonly called ?Sehjan? in India, is?one of the most cultivated and distributed plant species in the region. It?is a variable species that typically grows to 10 meters in height and has multiple uses as a vegetable, spice, medicinal plant and supply of culinary and cosmetic oil. All the parts of?plant have a range of vital nutrients and thus provide rich minerals, proteins, vitamins, ? -carotene, amino acids, and various phenolic contents. Moringa has been found to be of tremendous help?in fighting malnutrition especially in children and nursing mothers because of its high nutrition and vitamin density. More?importantly, its leaves can have nearly four times more either vitamin A, calcium, iron, vitamin C and potassium contents compared with well-known sources like carrots, milk, spinach, oranges and banana. In addition,?the protein quality in Moringa leaves is better than milk and eggs. This review provides an extensive discussion?on the phytochemicals, bioactivities, medicinal values, and nutritional value of M. oleifera.},
      keywords = {Moringa oleifera, Phytochemicals, Nutritional value, Glucosinolate, ?-Carotene},
      month = {March},
  }