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1703105 Vol 5 · Issue 7 Download Paper

Solid Dispersion-A Review

Nikhil Pasarkar Santosh Waghmare Hemant Kamble

Subject area: Science,Engineering and Technology  ·  Area of research: Pharmaceutical Sciences

Abstract

Solid dispersion is an effective way of improving the dissolution rate of poorly water soluble drugs and hence its bioavailability. The water soluble carriers used in preparation of solid dispersion enhance the dissolution rate of the poorly water soluble drug. The review article focuses on the methods of preparation, advantages, disadvantages and characterization of the solid dispersions.

References

[1] Sekiguchi K., Obi.N; Studies on absorption of eutectic mixtures: A comparison of the behaviour of eutectic mixtures of sulphathiazole and that of ordinary sulphathiazole in man; Chem. Pharm. Bull; 1961; 9; 866–872

[2] Singh et al; A review on solid dispersion; IJPLS; 2011; 2(9); 1078-1095

[3] Dixit AK., Singh RP; solid dispersion – A strategy for improving the solubility of poorly soluble drugs; IJRPBS; 2012; 3(2); 960-966

[4] Huda N.H., Saffoon N., Sutradhar K.B., Uddin R; Enhancement of Oral Bioavailability and Solid Dispersion: A Review; Journal of Applied Pharm Sci; 2011; 1; 13-20.

[5] Jain C.P., Sharma A; Solid dispersion: A promising technique to enhance solubility of poorly water-soluble drug; Int. J of Drug Delivery; 2011; 3; 149-170.

[6] Das S.K., Roy S., Kalimuthu Y., Khanam J., Nanda A; Solid Dispersions: An Approach to Enhance the Bioavailability of Poorly Water-Soluble Drugs; Int. J of Pharmacology and Pharmaceutical Technology; 1; 37 – 46.

[7] praveen kumar; solid dispersion – A review; Journal of pharmaceutical and scientific innovation; 2012; 1(3); 27-34

[8] Jaskirat et al; solubility enhancement by solid dispersion method: A review; Jornal of drug delivery & therapeutics; 2013; 3(5); 148-155

[9] Nikghalb et al; Solid Dispersion: Methods and Polymers to increase the solubility of poorly soluble drugs; Journal of Applied Pharmaceutical Science; 2012; 2(10); 170-175

[10] Kalia et al; solid dispersion- an approach towards enhancing dissolution rate; Int. J Pharm Sci; 2011; 3(4); 9-19

[11] Dixit et al; A review- solid dispersion,2014; World Journal of Pharmacy and Pharmaceutical Sciences; 3(9); 238-257

[12] Thakur et al; A review on solid dispersion; World Journal of Pharmacy and Pharmaceutical Sciences; 2014; 3(9); 173-187

How to cite this paper

Nikhil Pasarkar, Santosh Waghmare, Hemant Kamble "Solid Dispersion-A Review" Iconic Research And Engineering Journals Volume 5 Issue 7 2022 Page 70-75
Nikhil Pasarkar, Santosh Waghmare, Hemant Kamble "Solid Dispersion-A Review" Iconic Research And Engineering Journals, vol. 5, no. 7, Jan. 2022
Nikhil Pasarkar, Santosh Waghmare, Hemant Kamble (2022). Solid Dispersion-A Review. Iconic Research And Engineering Journals, 5(7).
Nikhil Pasarkar, Santosh Waghmare, Hemant Kamble "Solid Dispersion-A Review" Iconic Research And Engineering Journals, vol. 5, no. 7, Jan. 2022.
@article{1703105,
      author = {Nikhil Pasarkar, Santosh Waghmare, Hemant Kamble},
      title = {Solid Dispersion-A Review},
      journal = {Iconic Research And Engineering Journals},
      year = {2022},
      volume = {5},
      number = {7},
      pages = {70-75},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1703105.pdf},
      abstract = {Solid dispersion is an effective way of improving the dissolution rate of poorly water soluble drugs and hence its bioavailability.  The water soluble carriers used in preparation of solid dispersion enhance the dissolution rate of the poorly water soluble drug. The review article focuses on the methods of preparation, advantages, disadvantages and characterization of the solid dispersions.},
      month = {January},
  }