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Phenolics and Biocompounds Detected in Senna Alata Extract Using HPLC And GC-MS Analysis Respectively
Subject area: Science,Engineering and Technology · Area of research: Phytomedicine
Abstract
Senna alata is a plant found in Africa and other tropical regions of the world. Senna alata has been used traditionally for the treatment of different ailments. That is the reason why we investigated the presence of phenolics and other bioactive compound in the methanolic extract of Senna alata. Standard GC-MS and HPLC procedures were carried out on the extract. The results showed the presence of Methyl-4-(3-oxocyclohexyl)-butanoate with a peak number 13, retention time 14.782 and % area of 8.13, another detected bioactive with higher % area of 5.05 and retention time 16.467 was n-hexadecanoic acid methyl ester with a peak number 21 and Quercetrin 155.39 mg/100g > cinnamic acid 107.04 mg/100g > naringin 82.26 mg/100g > apigenin 66.75 mg/100g > caffeic acid 45.05 mg/100g > quercetin amongst others. In conclusion Senna alata extract contained important phenolics and other bioactive compounds that are of importance in health and disease.
How to cite this paper
@article{1703474,
author = {Eboh Abraham Sisein, Robert Owabhel Faith, Azibanasamesa Dumaro Charles},
title = {Phenolics and Biocompounds Detected in Senna Alata Extract Using HPLC And GC-MS Analysis Respectively},
journal = {Iconic Research And Engineering Journals},
year = {2022},
volume = {5},
number = {11},
pages = {249-252},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1703474.pdf},
abstract = {Senna alata is a plant found in Africa and other tropical regions of the world. Senna alata has been used traditionally for the treatment of different ailments. That is the reason why we investigated the presence of phenolics and other bioactive compound in the methanolic extract of Senna alata. Standard GC-MS and HPLC procedures were carried out on the extract. The results showed the presence of Methyl-4-(3-oxocyclohexyl)-butanoate with a peak number 13, retention time 14.782 and % area of 8.13, another detected bioactive with higher % area of 5.05 and retention time 16.467 was n-hexadecanoic acid methyl ester with a peak number 21 and Quercetrin 155.39 mg/100g > cinnamic acid 107.04 mg/100g > naringin 82.26 mg/100g > apigenin 66.75 mg/100g > caffeic acid 45.05 mg/100g > quercetin amongst others. In conclusion Senna alata extract contained important phenolics and other bioactive compounds that are of importance in health and disease.},
month = {May},
}