Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids

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@article{1704441,
      author = {Ugomma C. Onyeije, Chidera F. Onugha, Melford C. Egbujor, Chigbundu N. Emeruwa, Ifeanyi S. Amasiatu},
      title = {Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids},
      journal = {Iconic Research And Engineering Journals},
      year = {2023},
      volume = {6},
      number = {11},
      pages = {297-302},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1704441.pdf},
      abstract = {This research explores the synthesis of sulphonamide compounds from branched chained amino acid (BCAAs), their characterization and antimicrobial activities. The procedure involved a mild reaction of branched amino acids including valine, leucine and isoleucine with benzenesulfonyl chloride in an aqueous basic medium.  The characterization of the compounds was carried out using infra-red (IR), nuclear magnetic resonance (1HNMR) and ultraviolet (UV-Vis) spectroscopies. The synthesized compounds were tested for their antimicrobial activities against Staphylococcus aureus, Escherichia coli, and Candida albicans. They were found to be potential antimicrobial agents.},
      month = {May},
  }