This research explores the synthesis of sulphonamide compounds from branched chained amino acid (BCAAs), their characterization and antimicrobial activities. The procedure involved a mild reaction of branched amino acids including valine, leucine and isoleucine with benzenesulfonyl chloride in an aqueous basic medium. The characterization of the compounds was carried out using infra-red (IR), nuclear magnetic resonance (1HNMR) and ultraviolet (UV-Vis) spectroscopies. The synthesized compounds were tested for their antimicrobial activities against Staphylococcus aureus, Escherichia coli, and Candida albicans. They were found to be potential antimicrobial agents.
IRE Journals:
Ugomma C. Onyeije , Chidera F. Onugha , Melford C. Egbujor , Chigbundu N. Emeruwa , Ifeanyi S. Amasiatu
"Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids" Iconic Research And Engineering Journals Volume 6 Issue 11 2023 Page 297-302
IEEE:
Ugomma C. Onyeije , Chidera F. Onugha , Melford C. Egbujor , Chigbundu N. Emeruwa , Ifeanyi S. Amasiatu
"Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids" Iconic Research And Engineering Journals, 6(11)