Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids
Abstract
This research explores the synthesis of sulphonamide compounds from branched chained amino acid (BCAAs), their characterization and antimicrobial activities. The procedure involved a mild reaction of branched amino acids including valine, leucine and isoleucine with benzenesulfonyl chloride in an aqueous basic medium. The characterization of the compounds was carried out using infra-red (IR), nuclear magnetic resonance (1HNMR) and ultraviolet (UV-Vis) spectroscopies. The synthesized compounds were tested for their antimicrobial activities against Staphylococcus aureus, Escherichia coli, and Candida albicans. They were found to be potential antimicrobial agents.
Citations
IRE Journals:
Ugomma C. Onyeije, Chidera F. Onugha, Melford C. Egbujor, Chigbundu N. Emeruwa, Ifeanyi S. Amasiatu "Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids" Iconic Research And Engineering Journals Volume 6 Issue 11 2023 Page 297-302
IEEE:
Ugomma C. Onyeije, Chidera F. Onugha, Melford C. Egbujor, Chigbundu N. Emeruwa, Ifeanyi S. Amasiatu
"Synthesis, Characterisation and Antimicrobial Activities of Sulphonamides from Branched Chain Amino Acids" Iconic Research And Engineering Journals, 6(11)
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