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Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium

Dr. Yogita Shinde Vishal Telvekar

Subject area: Science,Engineering and Technology  ·  Area of research: Natural Plant Products

Abstract

The traditional Indian systems of medicine, specifically Ayurvedic and Siddha, frequently utilize the fruits and seeds of Semecarpus anacardium for treating cancer and various ailments due to their rich composition of secondary metabolites. This study aims to isolate, characterize, and identify phytochemicals from the seeds of Semecarpus anacardium. Phytochemicals were isolated using a reverse phase C18 column via preparative flash chromatography and characterized as catechol alkenyl derivatives through spectroscopic analyses, including HPLC, FTIR, UV, ??C NMR, ?H NMR, and LCMS. The identified structures of the isolated phytochemicals were determined to be 1,2-dihydroxy-3-pentadec-8-enylbenzene (A) and 1,2-dihydroxy-3-pentadeca-8,11-dienylbenzene (B). This research builds on existing literature regarding the medicinal applications of Semecarpus anacardium as a source of alternative therapies for various conditions. Numerous studies have highlighted its unique properties, demonstrating anti-arthritic, antimicrobial, antihelminthic, antioxidant, and anti-cancer activities attributed to these phytochemicals.

Keywords

Semecarpus anacardium, Catechol Derivative, Preparative Chromatography, TLC, LC-MS, FTIR

References

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How to cite this paper

Dr. Yogita Shinde, Vishal Telvekar "Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium" Iconic Research And Engineering Journals Volume 8 Issue 5 2024 Page 908-919
Dr. Yogita Shinde, Vishal Telvekar "Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium" Iconic Research And Engineering Journals, vol. 8, no. 5, Nov. 2024
Dr. Yogita Shinde, Vishal Telvekar (2024). Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium. Iconic Research And Engineering Journals, 8(5).
Dr. Yogita Shinde, Vishal Telvekar "Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium" Iconic Research And Engineering Journals, vol. 8, no. 5, Nov. 2024.
@article{1706571,
      author = {Dr. Yogita Shinde, Vishal Telvekar},
      title = {Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium},
      journal = {Iconic Research And Engineering Journals},
      year = {2024},
      volume = {8},
      number = {5},
      pages = {908-919},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1706571.pdf},
      abstract = {The traditional Indian systems of medicine, specifically Ayurvedic and Siddha, frequently utilize the fruits and seeds of Semecarpus anacardium for treating cancer and various ailments due to their rich composition of secondary metabolites. This study aims to isolate, characterize, and identify phytochemicals from the seeds of Semecarpus anacardium. Phytochemicals were isolated using a reverse phase C18 column via preparative flash chromatography and characterized as catechol alkenyl derivatives through spectroscopic analyses, including HPLC, FTIR, UV, ??C NMR, ?H NMR, and LCMS. The identified structures of the isolated phytochemicals were determined to be 1,2-dihydroxy-3-pentadec-8-enylbenzene (A) and 1,2-dihydroxy-3-pentadeca-8,11-dienylbenzene (B). This research builds on existing literature regarding the medicinal applications of Semecarpus anacardium as a source of alternative therapies for various conditions. Numerous studies have highlighted its unique properties, demonstrating anti-arthritic, antimicrobial, antihelminthic, antioxidant, and anti-cancer activities attributed to these phytochemicals.},
      keywords = {Semecarpus anacardium, Catechol Derivative, Preparative Chromatography, TLC, LC-MS, FTIR},
      month = {November},
  }