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Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium
Subject area: Science,Engineering and Technology · Area of research: Natural Plant Products
Abstract
The traditional Indian systems of medicine, specifically Ayurvedic and Siddha, frequently utilize the fruits and seeds of Semecarpus anacardium for treating cancer and various ailments due to their rich composition of secondary metabolites. This study aims to isolate, characterize, and identify phytochemicals from the seeds of Semecarpus anacardium. Phytochemicals were isolated using a reverse phase C18 column via preparative flash chromatography and characterized as catechol alkenyl derivatives through spectroscopic analyses, including HPLC, FTIR, UV, ??C NMR, ?H NMR, and LCMS. The identified structures of the isolated phytochemicals were determined to be 1,2-dihydroxy-3-pentadec-8-enylbenzene (A) and 1,2-dihydroxy-3-pentadeca-8,11-dienylbenzene (B). This research builds on existing literature regarding the medicinal applications of Semecarpus anacardium as a source of alternative therapies for various conditions. Numerous studies have highlighted its unique properties, demonstrating anti-arthritic, antimicrobial, antihelminthic, antioxidant, and anti-cancer activities attributed to these phytochemicals.
Keywords
Semecarpus anacardium, Catechol Derivative, Preparative Chromatography, TLC, LC-MS, FTIR
How to cite this paper
@article{1706571,
author = {Dr. Yogita Shinde, Vishal Telvekar},
title = {Isolation and Characterization of Catechol Derivative of Semecarpus Anacardium},
journal = {Iconic Research And Engineering Journals},
year = {2024},
volume = {8},
number = {5},
pages = {908-919},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1706571.pdf},
abstract = {The traditional Indian systems of medicine, specifically Ayurvedic and Siddha, frequently utilize the fruits and seeds of Semecarpus anacardium for treating cancer and various ailments due to their rich composition of secondary metabolites. This study aims to isolate, characterize, and identify phytochemicals from the seeds of Semecarpus anacardium. Phytochemicals were isolated using a reverse phase C18 column via preparative flash chromatography and characterized as catechol alkenyl derivatives through spectroscopic analyses, including HPLC, FTIR, UV, ??C NMR, ?H NMR, and LCMS. The identified structures of the isolated phytochemicals were determined to be 1,2-dihydroxy-3-pentadec-8-enylbenzene (A) and 1,2-dihydroxy-3-pentadeca-8,11-dienylbenzene (B). This research builds on existing literature regarding the medicinal applications of Semecarpus anacardium as a source of alternative therapies for various conditions. Numerous studies have highlighted its unique properties, demonstrating anti-arthritic, antimicrobial, antihelminthic, antioxidant, and anti-cancer activities attributed to these phytochemicals.},
keywords = {Semecarpus anacardium, Catechol Derivative, Preparative Chromatography, TLC, LC-MS, FTIR},
month = {November},
}