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Automated Prediction of Preeclampsia Using Artificial Intelligence
Subject area: Science,Engineering and Technology · Area of research: Artificial Intelligence and Biomedical Engineering
Abstract
This paper presents a system that builds artificial intelligence models for the automated prediction of the likelihood of occurrence of preeclampsia in pregnant women based on a suite of clinical measurements during the course of the pregnancy including proteinuria, amniotic fluid levels, fetal weight, gravida, parity, body mass index, systolic blood pressure, diastolic blood pressure, gestational age, presence or absence of diabetes, hemoglobin, history of hypertension and the age of the pregnant woman. The system is trained on publicly accessible preeclampsia datasets that could be augmented with locally sourced data for mitigation of bias, balance and robustness. The trained artificial intelligence models could be fine-tuned and integrated into preeclampsia prediction modules in a comprehensive artificial intelligence-driven healthcare system, saving lives and improving outcomes in pregnancy.
Keywords
Preeclampsia, Automated Disease Prediction, Artificial Intelligence (AI), Deep Learning (DL), Artificial Neural Network (ANN), TensorFlow, Healthcare System.
References
[1] World Health Organization (WHO) – Recommendations for Prevention and Treatment of Pre-eclampsia and Eclampsia: https://www.who.int/publications/i/item/9789241548335. Retrieved (2025).
[2] NHS – Pre-eclampsia: https://www.nhs.uk/conditions/pre-eclampsia/. Retrieved (2025).
[3] Nomura, A., Noguchi, M., Kometani, M., Furukawa, K., Yoneda, T. Artificial Intelligence in Current Diabetes Management and Prediction, Curr Diab Rep. 21(12):61 (2021).
[4] Kumar, Y., Koul, A., Singla, R., Ijaz, M. F. Artificial intelligence in disease diagnosis: a systematic literature review, synthesizing framework and future research agenda, Journal of Ambient Intelligence and Humanized Computing 14:8459–8486 (2023).
[5] Ansari, S., Shafi, I., Ansari, A., Ahmad, J., Shah, S. I. Diagnosis of liver disease induced by hepatitis virus using artificial neural network, IEEE Int Multitopic. https://doi.org/10.1109/INMIC.2011.6151515 (2011).
[6] Battineni, G., Sagaro, G. G., Chinatalapudi, N., Amenta, F. Applications of machine learning predictive models in the chronic disease diagnosis, J Personal Med. https://doi.org/10.3390/jpm10020021 (2020).
[7] Abdar, M., Yen, N., Hung, J. Improving the diagnosis of liver disease using multilayer perceptron neural network and boosted decision tree, J Med Biol Eng 38:953–965 (2018).
[8] Chaikijurajai, T., Laffin, L., Tang, W. Artificial intelligence and hypertension: recent advances and future outlook, Am J Hypertens 33:967–974 (2020).
[9] Fujita, S., Hagiwara, A., Otsuka, Y., Hori, M., Takei, N., Hwang, K. P., Irie, R., Andica, C., Kamagata, K., Akashi, T., Kumamaru, K. K., Suzuki, M., Wada, A., Abe, O., Aoki, S. Deep Learning Approach for Generating MRA Images From 3D Quantitative Synthetic MRI Without Additional Scans, Invest Radiol 55:249–256 (2020).
[10] Juarez-Chambi, R. M., Kut, C., Rico-Jimenez, J. J., Chaichana, L. K., Xi, J., Campos-Delgado, D. U., Rodriguez, F. J., Quinones-Hinojosa, A., Li, X., Jo, J. A. AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography, Clin Cancer Res 25(21):6329–6338 (2019).
[11] Nashif, S., Raihan, R., Islam, R., Imam, M. H. Heart Disease Detection by Using Machine Learning Algorithms and a Real-Time Cardiovascular Health Monitoring System, World Journal of Engineering and Technology Vol 6, No. 4 (2018).
[12] Chen, P. H. C., Gadepalli, K., MacDonald, R., Liu, Kadowaki, S., Nagpal, K., Kohlberger, T., Dean, J., Corrado, G. S., Hipp, J. D., Mermel, C. H., Stumpe, M. C. An augmented reality microscope with real time artificial intelligence integration for cancer diagnosis, Nat Med 25:1453–1457 (2019).
[13] Gouda, W., Yasin, R. COVID-19 disease: CT Pneumonia Analysis prototype by using artificial intelligence, predicting the disease severity, Egypt J Radiol Nucl Med 51(1):196 (2020).
[14] Han, Y., Han, Z., Wu, J., Yu, Y., Gao, S., Hua, D., Yang, A. Artificial Intelligence Recommendation System of Cancer Rehabilitation Scheme Based on IoT Technology, IEEE Access 8:44924–44935 (2020).
[15] Chui, C. S., Lee, N. P., Adeoye, J., Thomson, P., Choi, S. W. Machine learning and treatment outcome prediction for oral cancer, J Oral Pathol Med 49(10):977–985 (2020).
[16] Koshimizu, H., Kojima, R., Okuno, Y. Future possibilities for artificial intelligence in the practical management of hypertension, Hypertens Res 43:1327–1337 (2020).
[17] Kather, J. N., Pearson, A. T., Halama, N., Jäger, D., Krause, J., Loosen, S. H., Marx, A., Boor, P., Tacke, F., Neumann, U. P., Grabsch, H. I., Yoshikawa, T., Brenner, H., Chang-Claude, J., Hoffmeister, M., Trautwein, C., Luedde, T. Deep learning microsatellite instability directly from histology in gastrointestinal cancer, Nat Med 25:1054–1056 (2019).
[18] Kwon, J. M., Jeon, K. H., Kim, H. M., Kim, M. J., Lim, S. M., Kim, K. H., Song, P. S., Park, J., Choi, R. K., Oh, B. H. Comparing the performance of artificial intelligence and conventional diagnosis criteria for detecting left ventricular hypertrophy using electrocardiography, EP Europace 22(3):412–419 (2020).
[19] Khan, M. A. An IoT Framework for Heart Disease Prediction Based on MDCNN Classifier, IEEE Access 8:34717–34727 (2020).
[20] Oikonomou, E. K., Williams, M. C., Kotanidis, C. P., Desai, M. Y., Marwan, M., Antonopoulos, A. S., Thomas, K. E., Thomas, S., Akoumianakis, I., Fan, L. M., Kesavan, S., Herdman, L., Alashi, A., Centeno, E. H., Lyasheva, M., Griffin, B. P., Flamm, S. D., Shirodaria, C. Sabharwal, N., Kelion, A., Dweck, M. R., Van Beek, E. J. R., Deanfield, J., Hopewell, J. C., Neubauer, S., Channon, K. M., Achenbach, S., Newby, D. E., Antoniades, C. A novel machine learning-derived radiotranscriptomic signature of perivascular fat improves cardiac risk prediction using coronary CT angiography, Eur Heart J 40(43):3529–3543 (2019).
[21] Sabottke, C. F., Spieler, B. M. The Effect of Image Resolution on Deep Learning in Radiography, Radiology: Artificial Intelligence Vol. 2. No. 1, 2:e190015 (2020).
[22] Ekpar, F. E. A Comprehensive Artificial Intelligence-Driven Healthcare System, European Journal of Electrical Engineering and Computer Science, 8(3), Article 617. (2024).
[23] Ekpar, F. E. Diagnosis of Chronic Kidney Disease Within a Comprehensive Artificial Intelligence-Driven Healthcare System, International Journal of Advanced Research in Computer and Communication Engineering, 13(9). (2024).
[24] Ekpar, F. E. Image-based Chronic Disease Diagnosis Using 2D Convolutional Neural Networks in the Context of a Comprehensive Artificial Intelligence-Driven Healthcare System, Molecular Sciences and Applications, 4(13). (2024).
[25] Ekpar, F. E. Leveraging Generative Artificial Intelligence Recommendations for Image-based Chronic Kidney Disease Diagnosis, International Journal of Advanced Research in Computer and Communication Engineering, 14(1). (2025).
[26] Ekpar, F. E. A Novel Three-dimensional Multilayer Electroencephalography Paradigm, Fortune Journal of Health Sciences, 7(3). (2024).
[27] Ekpar, F. E. System for Nature-Inspired Signal Processing: Principles and Practice, European Journal of Electrical Engineering and Computer Science, 3(6), pp. 1-10, (2019).
[28] Ekpar, F. E. Nature-inspired Signal Processing, United States Patent and Trademark Office, US Patent Application Number: 13/674,035 (Filed: November 11, 2012, Priority Date: December 24, 2011), Document ID: US 20140135642 A1: Published: (2014).
[29] Abadi, M., Barham, P., Chen, J., Chen, Z., Davis, A., Dean, J., Devin, M., Ghemawat, S., Irving, G., Isard, M., Kudlur, M., Levenberg, J., Monga, R., Moore, S., Murray, D. G., Steiner, B., Tucker, P., Vasudevan, V., Warden, P., Wicke, M., Yu, Y., Zheng, X. TensorFlow: A System for Large Scale Machine Learning, Proceedings of the 12th USENIX Symposium on Operating Systems Design and Implementation (OSDI ’16). (2016).
[30] Pang, B., Nijkamp, E., Wu, Y. N. Deep Learning with TensorFlow: A Review, Journal of Educational and Behavioral Statistics. Vol. 45, Iss. 2. (2019).
[31] Kingma, D. P., Ba, J. L. Adam: A Method for Stochastic Optimization, International Conference on Learning Representations (ICLR) (2015).
[32] Zhang, Z. Improved Adam Optimizer for Deep Neural Networks,HYPERLINK "https://ieeexplore.ieee.org/xpl/conhome/8613196/proceeding"IEEE/ACM 26th International Symposium on Quality of Service (IWQoS) (2018). Link
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How to cite this paper
@article{1707427,
author = {Frank Edughom Ekpar},
title = {Automated Prediction of Preeclampsia Using Artificial Intelligence},
journal = {Iconic Research And Engineering Journals},
year = {2025},
volume = {8},
number = {9},
pages = {267-274},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1707427.pdf},
abstract = {This paper presents a system that builds artificial intelligence models for the automated prediction of the likelihood of occurrence of preeclampsia in pregnant women based on a suite of clinical measurements during the course of the pregnancy including proteinuria, amniotic fluid levels, fetal weight, gravida, parity, body mass index, systolic blood pressure, diastolic blood pressure, gestational age, presence or absence of diabetes, hemoglobin, history of hypertension and the age of the pregnant woman. The system is trained on publicly accessible preeclampsia datasets that could be augmented with locally sourced data for mitigation of bias, balance and robustness. The trained artificial intelligence models could be fine-tuned and integrated into preeclampsia prediction modules in a comprehensive artificial intelligence-driven healthcare system, saving lives and improving outcomes in pregnancy.},
keywords = {Preeclampsia, Automated Disease Prediction, Artificial Intelligence (AI), Deep Learning (DL), Artificial Neural Network (ANN), TensorFlow, Healthcare System.},
month = {March},
}