Influence of Family History Classifications in Cataract Occurrence Rate Among Local Residence of Imo State

References

[1] World Health Organization. Blindness and vision impairment. World Health Organization. 2023. https://www.who.int/news-room/fact-sheets/detail/blindness-and-visual-impairment.

[2] K. Pesudovs, V.C. Lansingh, J.H. Kempen, I. Tapply, A.G. Fernandes, M.V. Cicinelli, A. Arrigo, N. Leveziel, P.S. Briant, T. Vos, S. Resnikoff, H. R. Taylor, T. Sedighi, S. Flaxman, J. Steinmetz, & R. Bourne, Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020. Eye, 2024, pp. 1–15. https://doi.org/10.1038/s41433-024-02961-1

[3] A. Kubicka-Trząska,. Vision Disorders in Older People. Academic Press. 2019, pp. 412–425. https://doi.org/10.1016/B978-0-12-801238-3.11336-4.

[4] L. Morales-Brown, What to know about glaucoma and cataracts. Medicalnewstoday.com; Medical News Today, 2023, February 16. https://www.medicalnewstoday.com/articles/glaucoma-and-cataracts#causes

[5] I.K. Maji, S. Muhammad, S.I. Waziri, M.M. Rabiu, M. Yusuf, L. Muhammad, H.A. Isah, M.B. Adamu, & U.I. Alkali, an assessment of economic loss associated with cataract vision impairment for sustainable development in Borno state, Nigeria. Societal Impacts, 2024, 4, 100089. https://doi.org/10.1016/j.socimp.2024.100089

[6] C. L. Minkus, M. Pistilli, K. Dreger, T.D. Fitzgerald, A.R. Payal, R. Hosne Ara Begum, . Oktay Kaçmaz, D.A. Jabs, R.B. Nussenblatt, J.T. Rosenbaum, G.A. Levy-Clarke, H. Nida Sen, E.B. Suhler, J.E. Thorne, N.C. Bhatt, Stephen Foster, J.M. Buchanich, & J.H. Kempen, Risk of Cataract in Intermediate Uveitis. American Journal of Ophthalmology, 2021, 229, pp.200–209. https://doi.org/10.1016/j.ajo.2021.02.032.

[7] S.J. Bell, N. Oluonye, P. Harding, & M. Moosajee, Congenital cataract: a guide to genetic and clinical management. Therapeutic advances in rare disease, 2020, 1, 2633004020938061. https://doi.org/10.1177/2633004020938061.

[8] A. Shiels, & I.F. Hejtmancik, Inherited cataracts: Genetic mechanisms and pathways new and old. Experimental eye research, 2021, 209, 108662. https://doi.org/10.1016/j.exer.2021.108662.

[9] L. Khan, N. Shaheen, Q. Hanif, S. Fahad, & M. Usman, Genetics of congenital cataract, its diagnosis and therapeutics. Egyptian Journal of Basic and Applied Sciences, 2018, 5(4), pp. 252–257. https://doi.org/10.1016/j.ejbas.2018.07.001.

[10] A. Shiels, & I.F. Hejtmancik, Molecular Genetics of Cataract. Progress in molecular biology and translational science, 2015, 134, 203–218. https://doi.org/10.1016/bs.pmbts.2015.05.004

[11] X. Wu, E. Long, H. Lin, & Y. Liu, Prevalence and epidemiological characteristics of congenital cataract: a systematic review and meta-analysis. Scientific reports, 2016, 6, 28564. https://doi.org/10.1038/srep28564.

[12] T.I. Obianozie, S.J. Ozims, I.F. Eberendu, and G.N. Iwuoha, Prevalence of Cataract in Relation to Socio-demographic Factors: A Population Based Cross Sectional Study of Adults in Imo State Nigeria. International Journal of Research and Innovation in Applied Science, 2024 [online] IX(IX), pp.610–619. doi:https://doi.org/10.51584/ijrias.2024.909054.

[13] M.A. Adeniyi, R.K. Adewoye, G.O. Popoola, A. Babatunde, A.O. Ibrahim, & A.S. Azees, Awareness, prevalence and risk burden of cataract among adults in IDO/OSI local government area, a rural community of Ekiti state, southwest Nigeria. International Journal of Community Medicine and Public Health/International Journall of Community Medicine and Public Health, 2023, 10(9), pp. 3077–3085. https://doi.org/10.18203/2394-6040.ijcmph20232663

[14] H.E. Gali, R. Sella, and N.A. Afshari, Cataract grading systems. Current Opinion in Ophthalmology, 2019, 30(1), pp.13–18. doi:https://doi.org/10.1097/icu.0000000000000542.

[15] C. Rodrigue, A. Assavedo, K. Amedome, A. Issifou, A. Bio, F. Akponi, S. Monteiro, C. Abouki, & S. Alamou, EC OPHTHALMOLOGY EC OPHTHALMOLOGY Research Article Knowledge, Attitudes and Practices Regarding the Cataract among Adult in the Town of Parakou in 2020. 2021, Retrieved March 17, 2025, from https://ecronicon.net/assets/ecop/pdf/ECOP-12-00818.pdf.

[16] A.S. Alfaqeeh, R.Y. Bamjboor, & A.S. Bajaber, Risk Factors and Complications of Cataract Disease in Type Two Diabetic Patients in Taif City. World Family Medicine Journal/Middle East Journal of Family Medicine, 2020, 18(9), pp. 14–23. https://doi.org/10.5742/mewfm.2020.93851.

[17] J. Wang, J. Chen, W, Chen, Q. Wang, L, Zhao, R. Wang, Z, Liu, H. Chen, Q. Cao, X. Tan, Z. Lin, X. Li, J, Li, W. Lai, Y. Zhu, C. Chen, D. Zheng, M. Wu, Y. Han, Y., W. Chen, Incidence of and Risk Factors for Suspected Glaucoma and Glaucoma After Congenital and Infantile Cataract Surgery: A Longitudinal Study in China. Journal of Glaucoma, 2019, 29(1), pp. 46–52. https://doi.org/10.1097/ijg.0000000000001398.

[18] Shiels, A., & Hejtmancik, J. F, Genetics of human cataract. Clinical genetics, 2013, 84(2), pp. 120–127. https://doi.org/10.1111/cge.12182

@article{1707663,
      author = {Tochukwu Increase Obianozie,  Stanley James Ozims, Izuchukwu Francis Eberendu, Greg Ndubeze Iwuoha, Chike C. A. Okereke},
      title = {Influence of Family History Classifications in Cataract Occurrence Rate Among Local Residence of Imo State},
      journal = {Iconic Research And Engineering Journals},
      year = {2025},
      volume = {8},
      number = {9},
      pages = {1389-1395},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1707663.pdf},
      abstract = {Cataract is one of leading causes of visual impairments around the globe which is associated with genetic factors. The present study was designed as a descriptive cross-sectional study aimed at assessing the influence of family history classifications on cataract occurrence rate among adult residents in Imo State Nigeria. A multi-stage sampling method was used to sample 792 study participants across the state of study.  The presence of cataract was established using Lens Opacity Classification System (LOCS) III system. A slit lamp examination was performed to assess the severity of specific lens opacity. The participants were also assessed of family history of cataract using a study designed self-reported forms. Family history was classified into direct or first-degree relatives and indirect or second-degree relatives. The characteristics of the participants was described using statistical descriptive analysis technique such as frequency distribution table. Chi-square test was used to test for association between family history and occurrence of cataract. Further analysis includes logistic regression method used to compare the significant effects of factors of family history relatives. The results indicates that 200 (25.3%) reported having family history relatives with cataract. Significant association was found between cataract and family history (P=0.0001, ?2=73.42), with 98% lower odds found among the non-family history reported group (OR =0.022, 95% CI =0.0025 ? 0.0883). Interns of classifications of family history relatives, cataract was found highest among the direct or first-degree family relatives. It was also found to be most occurring if the family relative reported was a sister or a brother with up to four time more significant odds compared to non-direct relatives (OR= 4.11, 95% CI =1.040 ? 16.331). In conclusion, family history is significantly associated with cataract and contained greater risk among direct relatives such as brothers/ sister relatives. Detailed family history of cataracts classifications should adequately studied to identify the classes of familial cases at greater risk so as to minimise cost and enable the benefit from merits attached to early detection and treatments for the disease.},
      keywords = {Cataract, Visual Impairment, Family History, Direct Relatives},
      month = {March},
  }