Histological Effects of Ethanolic Leaf Extract of Musa paradisiaca on the Organs of Albino Wistar Rat

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@article{1707897,
      author = {Owo Ephraim Chinazom },
      title = {Histological Effects of Ethanolic Leaf Extract of Musa paradisiaca on the Organs of Albino Wistar Rat},
      journal = {Iconic Research And Engineering Journals},
      year = {2025},
      volume = {8},
      number = {10},
      pages = {570-575},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1707897.pdf},
      abstract = {The leaves of Musa paradisiaca commonly known as plantain are used for a number of purposes including wrappers for certain indigenous foods, animal feed and treatment of certain heath conditions due to their medicinal properties including antibacterial, antidote, astringent, anti-inflammatory, antidiarrheal, anthelminthic, antihypertensive, antiseptic, and cardiac demulcent. Despite the usefulness of Musa paradisiaca leaves especially for medicinal purposes, several studies have linked the ingestion of herbal remedies to deterioration of certain key organs such as kidney, liver, heart and the spleen. The current study therefore was designed to investigate the effect of the ethanolic leaf extract of Musa paradisiaca on the histology of the liver, kidney, heart and spleen of female Wistar albino rats. Ten (10) rats weighing 150-250 g were divided into two groups (Group A and Group B). Group A was administered distilled water only, while group B was administered the ethanolic leaf extract of Musa paradisiaca in appropriate concentrations depending on the animal weight for a period of 21 days. Photomicrograph results obtained from the histological study showed normal heart and spleen histology of the treated group administered ethanolic leaf extract of Musa paradisiaca. However, there were observed signs of necrosis in the liver and mild interstitial congestion in the kidney of the treated group administered ethanolic leaf extract of Musa paradisiaca. Result from the study points to the fact that the leaves of Musa paradisiaca may pose a threat on the kidney and liver.},
      keywords = {Extract, Histology, Organs, Photomicrograph, Musa-paradisiaca},
      month = {April},
  }