Potential Human Health Risk Assessment and Evaluation of Heavy Metals Contamination in Seafood from River Niger Across Ndoni Town in Onelga, Rivers State

References

[1] Abhyankar, L. N., Jones, M. R., Guallar, E., &Navas-Acien, A. (2012). Arsenic exposure and hypertension: a systematic review. Environ. Health Perspect, 120: 494-500.

[2] Abu, O.M.G and Nwokoma, G.C (2016). Bioaccumulation of Selected Heavy Metals in Water, Sediment and Blue Crab (Callinectes amnicola) from Bodo creek, Niger Delta, Nigeria. Journal of fisheries sciences.com. 10(3) : 77-83.

[3] Agrawal GD. (1999). Diffuse agricultural water pollution in India. Wat. Sci. Technol. 1999; 39(3):33–47.

[4] Agwu, K.K., Okoye, C.M.I., Okeji, M.C., and Clifford, E.O. (2018). Potential Health Impacts of Heavy Metal Concentrations in Fresh and Marine Water Fishes Consumed in Southeast, Nigeria. Pakistan Journal of Nutrition, 17: 647-653.

[5] Akoto, T.N, Bruce, G and Darke O. (2008) Heavy Metals Pollution Profiles in Streams serving. The Owabi Research. African Journal Environmental Science and Technology 2(11): 354-359

[6] Andra, S. S., Makris, K. C., Christophi, C. A., &Ettingerb, A. S. (2013). Delineating the degree of association between biomarkers of arsenic exposure and type-2 diabetes mellitus. Int. J. Hyg. Enviro. Health, 216: 35-49.

[7] Anisha, P. (2016). Role of chromium. Indian Journal of Pharmacy and Pharmacology, 3(11):17-23

[8] Anoop, K.R., Sundar, K.S.G., Khan, B.A. and Lal, S. (2009). Common Moorhen Gallinulachloropus in the diet of the African catfish Clariasgariepinus in Keoladeo Ghana National Park, India. Indian Birds; 5(2):22-23

[9] Argos, M., Kalra, T., Rathouz, P., Chen, Y., Pierce, B., Parvez, F., Islam T., Ahmed A., RakibuzZaman M., Hasan R., Sarwar G., Slavkovich V., van Geen A., Graziano J., Ahsan H. (2010). Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study. Lancet, 376: 252–8.

[10] ATSDR., 2005. Public health assessment guidance manual (Update). Department of Health and Human Service, Atlanta, Georgia. https://www.atsdr.cdc.gov/hac/phamanual/pdfs/phagm_final1-27-05.pdf.

[11] Azevedo, B. F., Furieri, L. B., Peçanha, F., Wiggers, G., FrizeraVassalo, P., RonacherSimões, M., Fiorim J., Rossi de Batista P., Fioresi M., Rossoni L., Stefanon I., Alonso M.J., Salaices M., Valentim Vassallo D. (2012). Toxic effects of mercury on the cardiovascular and central nervous systems. J. Biomed. Biotechnol., Vol. 2012, doi: 10.1155/2012/949048.

[12] Baird, C. 2002. Environmental Chemistry. Bookman, Porto Alegre, RS, Brazil (in Portuguese).

[13] Bakare-Odunola MT (2005) Determination of some metallic impurities present in soft drinks marketed in Nigeria. The Nig J Pharm 4: 51-54.

[14] Bakulski, K. M., Rozek, L. S., Dolinoy, D. C., Paulson, H. L., & Hu, H. (2012). Alzheimer’s disease and environmental exposure to lead: The epidemiologic evidence and potential role of epigenetics. Curr. Alzheimer Res., 9 (5): 563-573.

[15] Bender D.A. Nutritional Biochemistry of the Vitamins, Cambridge University Press 1992.

[16] Benoff, S., Jacob, A. and Herley I.R (2000) Male Infertility and Exposure to Lead and Calcium Human reproductive update 6, 107-112.

[17] Bernhoft, R. A. (2012). Mercury toxicity and treatment: A review of the literature. J. Environ. Public Health, Vol. 2012, doi:10.1155/2012/460508.

[18] Bhattacharjee, P., Chatterjee, D., Singh, K. K., &Giri, A. K. (2013). Systems biology approaches to evaluate arsenic toxicity and carcinogenicity: An overview. Int. J. Hyg. Environ. Health, 216: 574-586

[19] Biney, N., Đokić, M., Sedak, M. (1994) Metal content determination in four fish species from the Adriatic Sea. Food Chem. 124(3):1005-1010.

[20] Borchers, A., Teuber, S. S., Keen, C. L., & Gershwin, M. E. (2010). Food safety. Clinic Rev. Allerg. Immunol., 39: 95-141.

[21] Bose-O’Reilly, S., McCarty, K. M., Steckling, N., &Lettmeier, B. (2010). Mercury exposure and children’s health. Curr. Probl. Pediatr. Adolesc. Health Care, 40 (8): 186–215.

[22] Burbacher, T.M, C, Monnett, K.S. Grant and N.K. Mottet (1998). Methyl mercury effects on reproduction and offspring size at birth. ReprodToxicol 1(4) : 267-278.

[23] Calabrese EJ, Canada AT, Sacco C (1985) Trace elements and public health. Annual Review of Public health 6: 131-146.

[24] Carneiro, A.N, Noditi, M., Nilsson R, Natarajan AT. (2014) Genotoxic effects of sodium arsenite on human cells. Mutat Res.284:215–221.

[25] Ceccatelli, S., Dare, E., & Moors, M. (2010). Methylmercury-induced neurotoxicity and apoptosis. Chem. Biol. Interact., 188 (2): 301-308.

[26] Cheng, T.-F., Choudhuri, S., & Muldoon-Jacobs, K. (2012). Epigenetic targets of some toxicologically relevant metals: a review of the literature. J. Appl. Toxicol., 32:643–653.

[27] Dahi, I.J., Bjorkkjar, I.E., Graft Makia, M.K. and Idemensten, B. (2006). Fish more than just Omega 3. T.dsskr Nor laegeforen; 126:309 – 311.

[28] De Vizcaya-Ruiz, Kealotswe, E.S., and Sankwasa, K.S (2009). Pollution indicators in Gaboro

[29] Dœlsch, J.L, Landrum, P.F, Harold, B.L., William, B.H. (2006) editors. Bioavailability: Physical, Chemical, and Biological Interactions. Boca Raton, FL: CRC Press Inc.

[30] Donald B., Merton, D., Ruma, B. Stephe, R. and Vadiron, G., (2008) Redox Biochemistry John Wiley and sons Inc. Publication.

[31] Douglas A. Landis Stephen D. Wratten and Geoff M. Gurr. Annual Review of Entomology 2000 45:1, 175-201.

[32] Dybam, B., (2007). Field sampling and preparation subsamples of aquatic organisms for analysis of metals organochlorides. FAO. Fisher.Tech, 212, 1-13

[33] Ekweagwu, J.W.G., Warren, and Payne, J.F. (1992) Heavy Metals and Other Elements in Three Tissues of Cod, GadusMorhua, from the North Atlantic. Marine Pollution Bulletin, 24, pp. 452–458.

[34] El Nemr, Furtado, A.A.L., Albuquerque Leite, R.T., Leite, S.G., Pecanha, F.R.P. (2016). Effect of hydraulic retention Time on nitrification in an airlift Biological reactor. Brazilian J. Chemical engineering 15 p. 1-7.

[35] Enuneku, A., Omoruyi, O., Tongo, I., Ogbomida, E., Ogbeide, O., & Ezemonye, L. (2018). Evaluating the potential health risks of heavy metal pollution in sediment and selected benthic fauna of Benin River, Southern Nigeria. Applied Water Science, 8(8), 1–13. https://doi.org/10.1007/s13201-018-0873-9

[36] EPA. (2004). An examination of EPA risk assessment principles and practices. Environmental Protection Agency (EPA), Washington, DC. http://www.epa.gov/osa/pdfs/ratf-final.pdf.

[37] FAO/WHO. Evaluation of Certain Food Additives and Contaminants; World Health Organization Technical Report Series No.837; WHO: Geneva, Switzerland, 1993.

[38] Farombi, E.O., Adelowo, O.A., Ajimoko, Y.R. (2007) Biomarkers of oxidative stress and heavy metal levels as indicators of environmental pollution in African Cat fish (Clariasgariepinus) from Nigeria Ogun River. International Journal Environment Research Public Health 4, 158-165.

[39] Farzan, S. F., Karagas, M. R., & Chen, Y. (2013). In utero and early life arsenic exposure in relation to long-term health and disease. Toxicol. Appl. Pharmacol., 272: 384-390.

[40] Fatoki, M., Mathabatha, A. Copat, C., Ferrito, V., Grasso, A. and Ferrante, M. (2004) Heavy metal content and molecular species identification in canned tuna: Insights into human food safety. Mol. Med. Rep.15, 3430–3437.

[41] Fawole, O.O., Ogundiran, M.A., Ayandiran, T.A. and Olagunju, O.F. (2007). Mineral Composition in some selected fresh water fishes in Nigeria. African Journal for food safety; 9:52 – 58.

[42] FDA (Food and Drug Administration). (2001). Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Report of the Panel on Micronutrients. National Academy Press, Washington, DC Food and Drug Administration, Dietary supplements, Center for Food Safety and Applied Nutrition.

[43] Fessehaye, Yonas; El-bialy, Zizy; Rezk, Mahmoud A.; Crooijmans, Richard; Bovenhuis, Henk; Komen, Hans (2006). "Mating systems and male reproductive success in Nile tilapia (Oreochromisniloticus) in breeding hapas: A microsatellite analysis". Aquaculture. 256 (1–4): 148–158. doi:10.1016/j.aquaculture.2006.02.024

[44] Flora, S., Mittal, M., & Mehta, A. (2008). Heavy metal induced oxidative stress & it’s possible reversal by chelation therapy. Indian J. Med. Res., 128 (4): 501-503

[45] Food and Agriculture Organization/World Health Organization Evaluation of Certain Food Additives and Contaminants. (2014). Forty-first report of the Joint FAO/WHO Expert Committee on Food Additives.

[46] Froese, Rainer and Pauly, Daniel, eds. (2015). "Clariasgariepinus" in FishBase. March 2014 version.

[47] Galadima, A., N.U. Muhammad and GarbaZ.N. (2010). Spectroscopic investigation of heavy metals in waste water from University students halls of residence. Afr.Sci.; 11:165-170..

[48] Gallagher, C., &Meliker, J. (2010). Blood and urine cadmium, blood pressure, and hypertension: A systematic review and mata-analysis. Environ. Health Perspect., 118: 1676-84.

[49] Garcia-Rico L, Leyva-Perez J, Jara-Marini ME. (2007). Content and daily intake of copper, zinc, lead, cadmium, and mercury from dietary supplements in Mexico. Food Chemistry and Toxicology. 45:15991605.

[50] Gardner, R., Nyland, J., &Silbergeld, E. (2010). Differential immunotoxic effects of inorganic and organic mercury species in vitro. Toxicol. Lett., 198 (2): 182-190.

[51] Gleick, M. (1996). Heavy Metal Concentrations in Fish Tissues from the Northeast Mediterranean Sea, Bulletin of Environmental Contamination and Toxicology. 63, pp. 673–681

[52] Gorur, F.K., R. Keser, N. Akcay and S. Dizman, 2012. Radioactivity and heavy metal concentrations of some commercial fish species consumed in the Black Sea Region of Turkey. Chemosphere, 87: 356-361.

[53] Goyer, R. A. and Clarkson, T. W. (2001). Toxic effects of metals, In: C. D. Klaasen (Ed.), Casarett and Doullis Toxicology: The Basic Science of Poisons (sixth edition ed., pp. 811-867). New York: Mc-Graw-Hil.

[54] Grandjean, P., &Landrigan, P. J. (2014). Neurobehavioural effects of developmental toxicity. Lancet Neurol., 13: 330-38.

[55] Guertin J, Jacobs JA, Avakian CP (2004). Chromium (VI) Handbook. Boca Raton, FL:CRC Press,pp.800

[56] Guilarte, T. R., Opler, M., &Pletnikov, M. (2012). Is lead exposure in early life an environmental risk factor for schizophrenia? Neurobiological connections and testable hypotheses. Neurotoxicology, 33 (3): 560-574.

[57] Gundacker C, G. M. (2010). The relevance of the individual genetic background for the toxicokinetics of two significant neurodevelopmental toxicants: mercury and lead. Mutat. Res., 705 (2): 130-140.

[58] Guzzi G, L. P. (2008). Molecular mechanisms triggered by mercury. Toxicology, 244 (1), 1-12.

[59] Hall, A. (2002). Chronic arsenic poisoning. Toxicol. Lett., 128: 69-72.

[60] Hamed, B., Danadevi, K., Kaiser Jamil, Ahuja, Y.R., Visweswara, Rao. K., Ishap M. (2006) In vivo genotoxic effect of arsenic trioxide in mice using comet assay. Toxicol.;162:171–177.  

[61] Harvey, P. J., Handley, H. K. and Taylor M. P. (2015). Identification of the sources of metal lead contamination in drinking waters in north-eastern Tasmania using lead isotopic compositions, Environmental Science and Pollution Research; 22(16):12276–12288

[62] Heaney, B., (2003) “Sources of heavy metals and metalloids in soils,” in Heavy Metals in Soils: Trace Metals and Metalloids in Soils and their Bioavailability, pp. 11–50, Springer, Dordrecht, Netherlands,

[63] Hervé, G. Freedman, B. Environmental Ecology: The Ecological Effects of Pollution, Disturbance, and Other Stresses, 2nd ed.; Academic Press Inc.: San Diego, CA, USA, 1995; pp. 62–91, ISBN 0-12-266542-2.

[64] Horton, L. M., Mortensen, M. E., Iossifova, Y., Wald, M. M., & Burgess, P. (2013). What do we know of childhood exposures to metals (arsenic, cadmium, lead, and mercury) in emerging market countries? Int. J. Pediatr., Vol. 2013, doi: 10.1155/2013/872596.

[65] Ibrahim, A. A.; El-Zanfaly, H. T. (1980)."Boulti (Tilapia nilotica Linn.) fish paste 1. Preparation and chemical composition". ZeitschriftfürErnährungswissenschaft. 19 (3): 159–162. 

[66] International Occupational Safety and Health Information Centre, 1999.

[67] Iwegbue, C.M.A., S.O. Nwozo, E.K. Ossai and G.E. Nwajei. (2008). Heavy metal composition of some imported canned fruit drinks in Nigeria. Am. J. Food Technol., 3: 220-223.

[68] JECFA. Joint FAO/WHO. (1995). Expert committee on food additives. 64th Meeting, JECFA/64/SC, Codex Standard 2005193.

[69] John H Duffus “Heavy Metals” A Meaningless term (IUPAC Technical Report “Pure and Applied Chemistry, 2002,Vol 74.pp 793-807.

[70] Jomova, K., Jenisova, Z., Feszterova, M., Baros, S., Liska, J., Hudecova, D., Rhodes C.J., Valko M. (2011). Arsenic: toxicity, oxidative stress and human disease. J. Appl. Toxicol., 31: 95-107.

[71] Kamau, J.E., (2002) editor. The Heavy Elements: Chemistry, Environmental Impact and Health Effects. Oxford: Pergamon Press;.

[72] Karakadede, H., Oymak, S.A., and Unlu, E. (2004). Heavy metals in mullet, Liza abu, and catfish, Silurustriostegus from the Ataturk Dan Lake Euphrates. Turkey Environ. Int.; 30:183-188.

[73] Khandaker, M.U., Asaduzzaman, K., Nawi, S.M., Usman, A.R., and Amin, Y.M. (2015). Assessment of radiation and heavy metals risk due to the dietary intake of marine fishes (Rastrelligerkanagurta) from the straits of Malacca. PloS One, Vol. 10. 10.1371/journal.pone.0128790

[74] Khoshnood, Z., & Khoshnood, R. (2013). Health Risks Evaluation of Heavy Metals in Seafood. Transylvanian Review of Systematical and Ecological Research, 15(1), 137–144. https://doi.org/10.2478/trser-2013-0012.

[75] Kirpichtchikova, P.M. Zubenko, I.B (2010). Role of bottom sediments in the secondary pollution of aquatic environments by heavy metal compounds. Lakes and Reservoirs Res. Manage. 5(1): 11-21

[76] Kirschvink, A.M., Copat, C., Ferrito, V., Grasso, A. and Ferrante, M. (2006) Heavy metal content and molecular species identification in canned tuna: Insights into human food safety. Mol. Med. Rep.15, 3430–3437

[77] Koyashiki, G., Paoliello, M., &Tchounwou, P. (2010). Lead levels in human milk and children’s health risk: A Systematic Review. Rev. Environ. Health, 25 (3): 243-253.

[78] Lake, T., Rajeshkumar, S., & Li, X. (2018). Bioaccumulation of heavy metals in fi sh species from the Meiliang Bay ,. Toxicology Reports, 5(January), 288–295. https://doi.org/10.1016/j.toxrep.2018.01.007.

[79] Lambert M, Leven B.A, Green R.M.(2000). New methods of cleaning up heavy metal in soils and water; Environmental science and technology briefs for citizens; Manhattan, KS: Kansas State University; 2000.

[80] Lawrence W (2014) Toxic Metals and Detoxification. The Center for Development Inc., July 2014.

[81] Lee, C.M., Emmett, P.M., Emond, A.M. and Golding, J.A (2006) review of guidance on fish consumption in pregnancy: is it fit for purpose?. Public Health Nutr.21, 2149–2159

[82] Lentech, B.V (2012) culled from http://www.lentech.cm/recommended-daily-intake.htm

[83] LLobet, J.M., Falco, G., Casus, C., Texido, A. and Domingo, J.L. (2003) Concentration of Arsenic, Cadmium, Mercury and Lead in common foods and estimated daily intake by children, adolescents, adults, and seniors of Catalonia, Spain. J. Agric. Food chem.., 51, 838-842.

[84] Machiwa, Q. (2010) Seasonal investigation of trace element contents in commercially valuable fish species from the Black sea, Turkey. Food Chem Toxicol. 48(3):865-870

[85] Madkour, D. (2005) Detection the Pollution Status of Soils and Waters of Sawa Lake Area by Using Remote Sensing Techniques. Master’s Thesis, University of Al-Muthanna, Samawah, Iraq.

[86] Mansour, S. and Sidky, M. (2002). Ecotoxicological Studies: Heavy Metals Contaminating Water and Fish from Fayoum Governorate, Egypt. Food Chemistry; 78 (1)15-22.

[87] Martı´nez-Lo´ pez, E., Marı´a-Mojica, P., Martı´nez J.E., Calvo, J.F., Romero, D., Garcı´a-Ferna´ndez AJ (2005). Bull. Environ. Contam.Toxicol. 74: 477.

[88] Martin, K and Griswold, A. (2009) Cytogenetic evaluation of arsenic trioxide toxicity in Sprague-Dawley rats. Mut Res-Gen Tox Environ Mutagen. 587(1–2):126–133.

[89] Mason, L. H., Harp, J. P., & Han, D. Y. (2014). Pb Neurotoxicity: neuropsychological effects of lead toxicity. Biomed. Res. Int., Vol. 2014, doi: 10.1155/2014/840547.

[90] Menke, A., Muntner, P., Silbergeld, E., Platz, E., &Guallar, E. (2009). Cadmium levels in urine and mortality among U.S. adults. Environ. Health Perspect., 117: 190-6

[91] MERTZ, W., 1969. Chromium occurrence and function in biological systems. Physiol. Rev., 49: 163-239.

[92] Miller, S., Pallan, S., Gangji, A., Lukic, D., &Clase, C. (2013). Mercury-associated nephrotic syndrome: a case report and systematic review of the literature. Am. J. Kidney Dis., 62 (1): 135-138.

[93] Millward, R. Baramaki, T. and Ebrahimpour, M. (2008) “Acute toxicity bioassay of mercury and silver on Capoetafusca (black fish),” Toxicology and Industrial Health, vol. 28, no. 5, pp. 393–398,.

[94] Minoia, C., Rinchi, A., Pigatto, P., &Guzzi, G. (2009). Effects of mercury on the endocrine system. Crit. Rev. Toxicol., 39 (6): 538.

[95] Mishra, S., Bhalke, S., Saradhi, I.V., Suseela, B., Tripathi, R.M., Pandit, G.G. and Puranik, V.D., (2007). Trace metals and organometals in selected marine species and preliminary risk assessment to human beings in Thane Creek area, Mumbai. Chemosphere, 69, 972– 978.

[96] Mohammed, R., Alkhafaji, N. (2002) Distribution of heavy metals in parts of Diyala River, Iraq. Int. J. Sci. Res. 6, 879–884.

[97] Morais, A. (2012). Influence of lake chemistry and fish age on cadmium, copper and zinc concentrations in various organs of indigenous yellow perch (Percaflavescens). Cand. J. Fish. Aquat. Sci. 61: 702-716.

[98] Morais, S., & Pereira, F. G. e C. and M. de L. (2012). heavy Metals and Human Health. Environmental Health-Emerging issues and Practice (Vol. 324). https://doi.org/10.1111/j.1439-0264.1993.tb00363.x

[99] Mozaffarian, D., &Rimm, E. (2006). Fish intake, contaminants, and human health: evaluating the risks and the benefits. J. Am. Med. Assoc., 296: 1885-1899.

[100] NAS-NRC (1974) National Academy of Sciences-National Research Council. Food and Nutrition Board. Recommended Dietary allowances. Washington DC: National Academic Press.

[101] NAS-NRC (1975) National Academy of Sciences - National Research Council Division of Medical Sciences. Medical and environmental effects of pollutants: nickel. Washington DC: National Academic Press

[102] NAS-NRC (1982). National Academy of Sciences-National Research Council. Drinking Water and Health. Vol. 4. Washington DC: National Academic Press, p: 299.

[103] Nkpaa, KW; Essien, KB; Wegwu, MO (2013). Evaluation of Polycyclic Aromatic Hydrocarbon (PAH) concentrations in Crabs and Shrimps from Crude Oil Polluted Waters of Ogoniland in Rivers State, Nigeria.IOSR J. Environ. Sci. Toxicol. Food Technol. 4(6) 73-80not readily bioavailable. Environ. Sci. Technol. 43:5864-5870.

[104] Noël, L., Chafey, C., Testu, C., Pinte, J., Velge, P. and Guerin, T. (2011). Contamination levels of lead, cadmium and mercury in imported and domestic obsters and large crab species consumed in France: differences between white and brown meat. Journal of Food Composition and analysis; 24:368-375.

[105] O'Brien, T.J., S. Ceryak and S.R. Patierno, 2003. Complexities of chromium carcinogenesis: Role of cellular response, repair and recovery mechanisms. Mutat. Res./Fundam. Mol. Mech. Mutagen., 533: 3-36.

[106] Onisokyetu, A., Godwin, M., & Chinenye, N. G. (2016). Bioaccumulation of Selected Heavy Metals in Water, Sediment and Blue Crab (Callinectes amnicola) from Bodo Creek, Niger Delta, Nigeria, 10(3), 77–83.

[107] Orloff , K., Mistry , K., & Metcalf , S. (2009). Biomonitoring for environmental exposures to arsenic. J. Toxicol. Environ. Health, 12: 509-24.

[108] Osei, Y.A. (1992), New school chemistry, FEP Publishing pp (259-268).

[109] Osman, A., Wuertz, S., Mekkawy, I., Exner, H. and Kirschbaum, F. (2007). Lead Induced Malformations in Embryos of the African Catfish Clariasgariepinus. Environmental Toxicology; 22(4):375-389.

[110] Pandey, R. (2006). Fish Mercury Distribution in Massachusetts, USA Lakes” Environmental Toxicology and Chemistry, 18 (7) pp. 1370–1379.

[111] Park, J.-D., & Zheng, W. (2012). Human exposure and health effects of inorganic and elemental mercury. J. Prev. Med. Public Health, 45: 344-352

[112] Parkin, D. M., Nambooze, S., Wabwire-Mangen, F. and Wabinga, H. R. (2010). Changing cancer incidence in Kampala, Uganda, 1991-2006, International Journal of Cancer, 126, 1187-1195.

[113] Patrick-Iwuanyanwu, K.C., Obasi, M.O., Ogbo, A.B; Egbuna, C. (2020). Human Health Risk Assessment of Heavy Metals via Consumption of Selected Seafoods from Three Different Open Markets in Bayelsa State. Annals of Biological Sciences. 8 (1):1-9

[114] Peña-Mendoza, B.; J. L. Gómez-Márquez; I. H. Salgado-Ugarte; D. Ramírez-Noguera. (2005). "Reproductive biology of Oreochromisniloticus (Perciformes: Cichlidae) at Emiliano Zapata dam, Morelos, Mexico". Revista de Biología Tropical. 53 (3/4): 515–522. 

[115] Petkovšek, S.A.S., Grudnik, Z.M. and Pokorny, B., (2011). Heavy metals and arsenic concentrations in ten fish species from the Šalek lakes (Slovenia): assessment of potential human health risk due to fish consumption. Environmental Monitoring and Assessment, 184, 2647-2662

[116] Pyszel, A., Wrobel, T., Szuba, A., &Andrzejak, R. (2005). Effect of metals, benzene, pesticides and ethylene oxide on the haematopoietic system. Med. Pr., 56 (3): 249-255.

[117] Qui XX, Huang DF, Cai SX, Chen F, Ren ZG, Cai YC (2000). Investigations on seafoods pollution and pollution sources and its control in Fuzhou, Fujian Province. Fujian J. Agric. Sci. 15: 16-21

[118] Radojevic, M and Bashkin, V.N. (1999). “PracticalEnvironmental Analysis”, Royal Society of Chemistry, Cambridge, 466.

[119] Ramessur, A. (2002) Reference Materials in Analytical Chemistry: A Guide for Selection and Use, illustrated ed.; Springer Science & Business Media: Berlin, Germany, pp. 25–55, ISBN 3642569862, 9783642569869.

[120] Rashed, M.N., 2001. Egypt monitoring of environmental heavy metals in fish from Nasser Lake. Environ. Int., 27: 27-33.

[121] Raymond, A., Wuana, F.E. and Okienimen (2011). Heavy Metals in contaminated soils; A Review of Sources, Chemistry, Risk and Best Available Strategies for Remediation. International Scholarly Research Network, 2011:1-20.

[122] Rice, K. M., Walker Jr, E. M., Wu, M., Gillette, C., & Blough, E. R. (2014). Environmental mercury and its toxic effects. J. Prev. Med. Public Health, 47: 74-83.

[123] Rodríguez-Barranco, M., Lacasaña, M., Aguilar-Garduño, C., Alguacil, J., Gil, F., GonzálezAlzaga, B., Rojas-García A. (2013). Association of arsenic, cadmium and manganese exposure with neurodevelopment and behavioural disorders in children: A systematic review and meta-analysis. Sci. Total Environ., 454-455: 562-577.

[124] Rosado, J., Ronquillo, D., Kordas, K., Rojas, O., Alatorre, J., Lopez, P., Garcia-Vargas G., Del Carmen Caamaño M., Cebrián M.E., Stoltzfus R.J. (2007). Arsenic exposure and cognitive performance in Mexican schoolchildren. Environ. Health Perspect., 115: 13711376

[125] Ruxton, F.K., Keser, R., Akcay, N., Dizman, S. (2005) Radioactivity and heavy metal concentrations of some commercial fish species consumed in the Black Sea Region of Turkey. Chemosphere 87(4):356-361.

[126] Sabath, E., & Robles-Osorio, M. L. (2012). Renal health and the environment: heavy metal nephrotoxicity. Nefrologia, 32 (3): 279-86.

[127] Saria, A. (2016) Determination of metals in tuna species and bivalves from Alexandria, Egypt. Egypt J Aquat Res. 40(1):9- 17.

[128] Schwartz, G., Yasova, D., & Ivanova, A. (2003). Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III. Diabetes Care, 26: 468-470.

[129] Scragg, A. (2006). Environmental Biotechnology, Oxford University Press, Uk, 2nd Edition.

[130] Shafiq-ur-Rehman. (2013). Effect of lead on lipid peroxidation, phospholipids composition, and methylation in erythrocyte of human. Biol. Trace Elem. Res., 154: 433-439.

[131] Siebe, C., 1995. Heavy metal availability to plants in soil irrigated with waste water from Mexico city. Wat. Res. 32 (12), 29–34.

[132] Sindiku, O.K and Osibanjo, O. (2011). S ome priority heavy metals in children toys imported at Nigeria. Journal of Toxicology and Environmental Health Sciences, 3(4) : 109-115.

[133] Singh A, Sharma RK, Agarwal M, Marshall FM. (2010). Risk assessment of heavy metal toxicity through contaminated seafoods from waste water irrigated area of Varanasi, India. Trop Ecol. 51:375387.

[134] Sivaperumal P, Sankar TV, Viswanathan PG (2007) Heavy metal concentrations in fish, shellfish and fish products from internal markets of India vis-a-vis international standards. Food Chemistry 102: 612-620.

[135] Smedley, P., &Kinniburgh, D. (2002). A review of the source, behaviour and distribution of arsenic in natural waters. Appl. Geochem., 17: 517-68.

[136] Smith, J.A., Nelson, R.H., Casto, B.C. (2010) In-vitro neoplastic transformation of Syrian hamster cell by lead acetate and its relevance to environmental carcinogenesis. Br J Cancer. 1978;38:452–455

[137] Stea, F., Bianchi, F., Cori, L., &Sicari, R. (2014). Cardiovascular effects of arsenic: clinical and epidemiological findings. Environ. Sci. Pollut. Res., 21: 244–251

[138] Steften, W. (2006). Fresh water fish wholesome foodstuff. Journal of Agricultural Science4:320 – 328.

[139] Sternberg, R. von, and N. Cumberlidge. 2001. On the heterotreme-thoracotreme distinction in the Eubrachyura De Saint Laurent, 1980 (Decapoda: Brachyura). Crustaceana 74: 321–338.

[140] Tellez-Plaza, M., Jones, M. R., Dominguez-Lucas, A., Guallar, E., &Navas-Acien, A. (2013). Cadmium exposure and clinical cardiovascular disease: a systematic review. Curr. Atheroscler. Rep., 15 (10): 356-371.

[141] Toguyeni, A; Fauconneau, B; Boujard, T; Fostier, A; Kuhn, E; Mol, K; Baroiller, J (1997). "Feeding behaviour and food utilisation in tilapia, OreochromisNiloticus: Effect of sex ratio and relationship with the endocrine status". Physiology & Behavior. 62 (2): 273–279. 

[142] Toyokuni, N. (2009) Microwave Digestion of Fish Tissues and Determination of Cu, Se, and Hg by Atomic Absorption Spectrometry. International Journal of Environmental Analytical Chemistry. 72 (3), pp. 205–216.

[143] Turkmen, M. and C. Ciminli, 2007. Determination of metals in fish and mussel species by inductively coupled plasma-atomic emission spectrometry. Food Chem., 103: 670-675.

[144] Ullah, A. K. M. A., Maksud, M. A., Khan, S. R., Lutfa, L. N., & Quraishi, S. B. (2017). Dietary intake of heavy metals from eight highly consumed species of cultured fish and possible human health risk implications in Bangladesh. Toxicology Reports, 4(July), 574–579. https://doi.org/10.1016/j.toxrep.2017.10.002

[145] United States Environmental Protection Agency Assessing Human Health Risks from Chemically Contaminated Fish and Shellfish: A guidance manual. From: nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=2000DGLF.txt Accessed: Oct 2014.

[146] United States Environmental Protection Agency Mid-Atlantic Risk Assessment (2014). Human Health Risk Assessment. From: www.epa.gov/reg3hwmd/risk/human/index.htm Accessed: Oct 2014.

[147] United States Environmental Protection Agency, (2011). Risk-based Concentration Table. United State Environmental Protection Agency, Washington, DC.

[148] Usero, J., C. Izquierdo, J. Morillo and I. Gracia. (2003). Heavy metals in fish (Solea vulgaris, Anguilla anguilla and Liza aurata) from salt marshes on the Southern atlantic coast of Spain. Environ. Int., 29: 949-956.

[149] Usman, N., Biswas, A.K., Qureshi, T.A., Borana, K., Virha, R. (2013). Bioaccumulation of heavy metals in fish tissues of a freshwater lake of Bhopal. Environ. Monit. Assess. 160: 267-267

[150] Vanguard (2014) FG crashes fish prices to affordable levels. Vanguard news

[151] Vidjani, A., Pangborn, J., Vodjani, E., & Cooper, E. (2003). Infections, toxic chemicals and dietary peptides binding to lymphocyte receptors and tissue enzymes are major instigators of autoimmunity in autism. Int. J. Immunopathol. Pharmacol., 16 (3): 189-199.

[152] VitaliySemenchenko, A.B.C., Tatiana L. and Vladimir R. (2008). A new record of the North American gastropod Physellaacuta from the Neman River Basin, Belarus. Aquatic Invasions; 3:359-360.

[153] Vogiatzoglou, P. Jack, R., Hutcheson, M.S., West, C.R., and Pancorbo, O. (2009) Fish Mercury Distribution in Massachusetts, USA Lakes. Environmental Toxicology and Chemistry 18 (7), pp. 1370–1379.

[154] W.H.O., (2009) Toxic and essential trace elemental contents in fish species from the Black Sea, Turkey. Food Chem Toxicol. 47(8):1785-1790.

[155] Wang, B., & Du, Y. (2013). Cadmium and Its Neurotoxic Effects. Oxid. Med. Cell Longev., Vol. 2013, doi: 10.1155/2013/898034.

[156] Wardman, H.A. (2007) Fish: It’s Usually the Last Meat People Give Up, Maybe it Should be the First. New England Journal of Medicine. 33(2), pp. 977.

[157] Weber, M., Turkmen, A., Tepe, Y., Ates, A., Gokkus, K. (2008) Determination of metal contaminations in sea foods from Marmara, Aegean and Mediterranean seas: Twelve fish species. Food Chem. 108(2):794-800.

[158] WHO/FAO, “WHO technical report series No 505 (1989). Evaluation of certain food additives and the contaminants, mercury, lead and cadmium for environment monitory report No 52 center for environment,” Tech. Rep., Fisheries And Aquaculture Science Lowest Tofit UK.

[159] Yujun Y, Zhifeng Y, Shanghong Z (2011) Ecological risk assessment of heavy metals in sediment and human health risk assessment of heavy metals in fishes in the middle and lower reaches of the Yangtze River basin. Environmental Pollution 159: 2575-2585

[160] Zallt, H. Yousuf, and M.S. El-Shahawi. (2007) Trace Metals in LethrinusLentjan Fish from Arabian Gulf: Metal Accumulation in Kidney and Heart Tissues. Bulletin of Environmental Contamination and Toxicology. 62, pp. 293–300

@article{1710493,
      author = {Assayomo Ebimobowei, Godwin Ebiowei Dele, Umueni Uchenna Elizabeth, Ogbo Ahiakwo Bright},
      title = {Potential Human Health Risk Assessment and Evaluation of Heavy Metals Contamination in Seafood from River Niger Across Ndoni Town in Onelga, Rivers State},
      journal = {Iconic Research And Engineering Journals},
      year = {2025},
      volume = {9},
      number = {3},
      pages = {581-600},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1710493.pdf},
      abstract = {Anthropogenic Sources tend to elevate level of heavy metals in the water bodies. The seafood bio accumulates these metals often times within their body system. This study evaluated the quantities of Lead (Pb), Cadmium (Cd), Chromium (Cr), Nickel (Ni), Copper (Cu), Iron (Fe), Zinc (Zn) and Mn from seafood specifically Periwinkle, Shrimp and Crab obtained from River Niger across Ndoni town in Rivers State. The result obtained was employed in assessing the human health risk. Ninety six samples comprising of Periwinkle, Shrimp and Crab were digested and tested using Flame (F-AAS).The result reflected that the levels of Pb, Cd, Cr, Ni, Cu,  Fe, Zn, and Mn ranged from 0.040 ? 0.002to 0.817 ? 0.001 mg/kg; 0.002 ? 0.001 to 0.064 ? 0.001 mg/kg; 0.386 ? 0.005 to 3.422 ? 0.011 mg/kg; 0.670 ? 0.008 to 4.760 ? 0.015 mg/kg; 2.154 ? 0.003 to 9.108 ? 0.003 mg/kg; 5.120 ? 0.012 to 512.31 ? 0.006 mg/kg; 6.137 ? 0.009 to 18.337 ? 0.020 mg/kg; and 2.476 ? 0.029 to 8.322 ? 0.026 mg/kg correspondingly. The concentration of Cr surpassed the permissible values. The results of the human health risk assessment pointed out that it is safe and free from non-carcinogenic carcinogenic risks. However, Cr should be checked to prevent impending health risk from its accumulation in the body.},
      keywords = {Heavy metals; seafood; potential; health, risk assessment; Ndoni.},
      month = {September},
      doi = {https://doi.org/10.64388/IREV9I3-1710493-739}
  }