Synthesis, Characterization and Antimicrobial Evaluation of Mixed Ligand Complexes of Dimethiglyoxime and Barbitone with Nickel (II) Ions in Water-Methanol Medium

References

[1] Abdulhamid, D., Ahmad A.S, Muhammed, A.T and Ali, MA (2016). Synthesis, characterization and antimicrobial studies of Ampicillin complexes. American Chemical Science Journal, 12(4):15.

[2] Adkhis, A.S. Dejebbar- Sidi, O, Benali- Baittich, A Khadri, M, and Bouet, G. (2003).Synthesis, characterization and electrochemical behavior of mixed ligand complexes of CO(II) with dimethylglyoxime and some amino acid .syth.React.Inorg.Met Org.Chem…33(1):35 50

[3] Asegboyin.J.N, Oyeka, E.E, Babalian, I and Olapareke, O. (2018). Novel synthesis of metal complexes and antimicrobial activities j. Chem. Soc. Nigeria. 43{33}:537-547.

[4] Bamigboye M.O, Obaleye, J A and Aroon, I.Y (2011).Synthesis and characterization of mixed Sulphate-Ampicillin complexes. Journal of Applied science and Environmental Management, University of port Harcourt.18(12):203-206

[5] Coey, J.M.D, Skumryev,V, Gallagher (1999).Rare-earth metals::IOs gadolinium really ferromagnetic in nature.401(6748)000:35-36

[6] Cotton, F.A and Wilkinson, G, A, (1986).Advanced Inorganic Chemistry, A Comprehensive Text 3rd Edn.Wiley Eastern LTD, Singapore: 8882-916.

[7] Finley E (1919) Veronal’ ’The American Material Medical, Y Therapeutics and pharmacology. P.115, Retrieved 25 July 2015.

[8] Girolami, G.S, Rauchfuss, T.B; Angelica, R.J (1999). Synthesis and Technique in Inorganic Chemistry: A Laboratory Manual (3rd Ed). Pp 213-215.

[9] Hamida, I. (1994). Chemical and antibacterial studies of mixed ligand transition metal complexes, Ph.D. Thesis, Department of Pharmaceutical Chemistry, University of Karachi, pp 32-33,105-130.

[10] Lee (2009). Advanced inorganic chemistry textbook

[11] Nakamoto, K. (1986).Infrared and Raman Spectra of Inorganic and coordination compounds 3rd edn…John Wiley and Sons New York. Pp;-1977.205-233.

[12] Olagboye 2015,Mixed ligand complexes of cobalt (ii) Barbitone in aqueous medium and their biological activities, Chemistry and Material Science Research.7(4) :129-133

[13] Osunlaja, A.A., Ndahi, N.P, Ameh Adetoro, A. (2011). Synthesis, physio-chemical properties of CO (II), and Cu (II) mixed-ligand complexes of Dimethylglyoxime .Research Journal of Applied Science, Engineering and Technology. 3(II):1233-1238

[14] Peter, Kolawole (2005). Reported the use of metal complexes in fighting in microbial infections ’Sanap S.V and Pati R.M, DeS.J, pharm. SCI, 2(1), 1 (2013).

[15] Sharma, C.L.., De, T.K and Jain, P.K (1981). Characterization of mixed – ligand complexes of some bivalent transition metal imides with polyamides. J. Inorganic Nuc. Chem 43(8):1811-1815.

[16] Warra, A.A (2011). Transition metal complexes and their application in drugs and cosmetics- A review Journal of chemical and pharmaceutical Research, 3(4):951-958.

@article{1711455,
      author = {O. M. Afolabi, S. A. Olagboye, S. A. Adeyemi, O. Aworetan},
      title = {Synthesis, Characterization and Antimicrobial Evaluation of Mixed Ligand Complexes of Dimethiglyoxime and Barbitone with Nickel (II) Ions in Water-Methanol Medium},
      journal = {Iconic Research And Engineering Journals},
      year = {2025},
      volume = {9},
      number = {4},
      pages = {1321-1326},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1711455.pdf},
      abstract = {Mixed ligand complexes of Dimethyglyoxime (DMG) and barbitone with Nickel (II) ion in water-methanol medium at different ratio concentration were carried out by direct mixing method. The synthesis of Ni(II) complexes with DMG and Babitone were characterized on the basis of physical properties such as colour,% yield, melting point and % metal analysis using complexometric  titration method  and as well as spectroscopy data of analysis which include the UV-Visible and FTIR-Spectroscopy. The result of physical properties of the Ni (II) complexes revealed that the metal complexes were pure, non-hygroscopic in nature with sharp melting points and reasonable percentage yields. The solubility tests   result showed that Ni (II) Dmg complexes and its mixed ligand were non-electrolyte and non-polar in nature. The spectroscopic results presumed that coordination of Ni (II) to the free ligand DMG was through the oxygen atom of oxime and nitogen atom of Barbitone mixed ligand. The results of anti-microbial analysis predicted that mixed ligand complexes performed   fairly against the selected pathogens while the ligands were totally inactive.},
      keywords = {Mixed ligand ,  Dimethylglyoxime, barbitone, Nickel(II).},
      month = {October},
      doi = {https://doi.org/10.64388/IREV9I4-1711455-8478}
  }