Stem Cell Exhaustion and Reduced Tissue Repair in Ageing, Cancer, and Degenerative Diseases
Abstract
Stem cell exhaustion - the loss of functional stem cell numbers and their regenerative capacity - is a central trademark for cellular ageing and a key contributor to impaired and affected tissue repairs in many degenerative diseases and cancer. This paper will discuss the cellular and molecular understanding of the mechanisms that drive stem dysfunction (DNA damage, condensation of telomeres) and examine how exhaustion contributes to degenerative diseases such as Alzheimer's.
Citations
IRE Journals:
Aarush Aditya Parulkar, Akhilesh Chowdary Korrapati "Stem Cell Exhaustion and Reduced Tissue Repair in Ageing, Cancer, and Degenerative Diseases" Iconic Research And Engineering Journals Volume 9 Issue 8 2026 Page 1683-1687
IEEE:
Aarush Aditya Parulkar, Akhilesh Chowdary Korrapati
"Stem Cell Exhaustion and Reduced Tissue Repair in Ageing, Cancer, and Degenerative Diseases" Iconic Research And Engineering Journals, 9(8)
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