Synthesis, Characterization and Antimic6 Activity of Some Pyrazole Derivative
  • Author(s): Bushra Taj; Santosh Kumar Shukla
  • Paper ID: 1717424
  • Page: 758-762
  • Published Date: 08-05-2026
  • Published In: Iconic Research And Engineering Journals
  • Publisher: IRE Journals
  • e-ISSN: 2456-8880
  • Volume/Issue: Volume 9 Issue 11 May-2026
Abstract

Objective: The present study aimed to evaluate the antibacterial activity of different Pyrazole derivatives (4A–E) and screened against selected pathogenic microorganisms and to compare their efficacy with a standard antibiotic. Materials and Methods: The antibacterial activity of the developed formulations was assessed against Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus using the zone of inhibition method. The results were compared with the standard drug tetracycline to determine relative efficacy. Results: Among all formulations, 5B and 5C demonstrated the highest antibacterial activity, exhibiting significant zones of inhibition against all tested microorganisms. Strong activity was particularly observed against Pseudomonas aeruginosa and Staphylococcus aureus, indicating broad-spectrum effectiveness. Other formulations showed moderate to low activity, while some exhibited no inhibition against Klebsiella pneumoniae.

Keywords

Antibacterial, Pyrazole, Klebsiella Pneumoniae.

Citations

IRE Journals:
Bushra Taj, Santosh Kumar Shukla "Synthesis, Characterization and Antimic6 Activity of Some Pyrazole Derivative" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 758-762 https://doi.org/10.64388/IREV9I11-1717424

IEEE:
Bushra Taj, Santosh Kumar Shukla "Synthesis, Characterization and Antimic6 Activity of Some Pyrazole Derivative" Iconic Research And Engineering Journals, 9(11) https://doi.org/10.64388/IREV9I11-1717424