Current Volume 9
Formulation and Evaluation of a Polyherbal Anti-Acne Face Wash Containing Matricaria chamomilla and Rubia cordifolia
Abstract
Acne vulgaris is among the most prevalent dermatological conditions worldwide, affecting approximately 85% of adolescents and a significant proportion of adults. The increasing resistance to conventional antibiotics and adverse effects associated with synthetic formulations have driven renewed interest in herbal alternatives. The present investigation aimed to formulate and evaluate a polyherbal anti-acne face wash incorporating extracts of Matricaria chamomilla (German chamomile) and Rubia cordifolia (Indian madder/Manjistha) for their synergistic antimicrobial, anti-inflammatory, and sebum-regulating properties. Four formulations (F1–F4) were prepared with varying concentrations of herbal extracts and assessed for physicochemical parameters including pH (5.8–6.5), viscosity (2,200–3,100 cP), foam stability (82–96%), and skin irritation. Antimicrobial efficacy against Staphylococcus epidermidis and Propionibacterium acnes was evaluated using the agar diffusion method. Formulation F3 demonstrated superior performance with a zone of inhibition of 18.4 mm against P. acnes and 16.2 mm against S. epidermidis, comparable to the positive control (ciprofloxacin, 21.0 mm). All formulations passed stability studies at 40°C/75% RH for 90 days. The optimized formulation showed no skin sensitization in patch test studies. These findings support the therapeutic potential of the polyherbal face wash as a safe, effective, and sustainable approach to managing acne vulgaris.
Keywords
Matricaria chamomilla, Rubia cordifolia, Acne vulgaris, Polyherbal, Face wash, Antimicrobial, Zone of inhibition
Citations
IRE Journals:
Abhishek Verma, Prof. (Dr). Amresh Gupta, Km. Tanya Srivastava "Formulation and Evaluation of a Polyherbal Anti-Acne Face Wash Containing Matricaria chamomilla and Rubia cordifolia" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 921-925 https://doi.org/10.64388/IREV9I11-1717486
IEEE:
Abhishek Verma, Prof. (Dr). Amresh Gupta, Km. Tanya Srivastava
"Formulation and Evaluation of a Polyherbal Anti-Acne Face Wash Containing Matricaria chamomilla and Rubia cordifolia" Iconic Research And Engineering Journals, 9(11) https://doi.org/10.64388/IREV9I11-1717486
About IRE Journals
IRE Journals is an open access online journals established with an aim to publish high quality of research work in various diciplines. We have more than 6 years in publications. Over 2500+ papers already published.
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