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1717614PublishedVol 9 · Issue 11

Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease

Subodh Kumar Hakim Singh Rajput Dr. Amresh Gupta

Subject area: Biological & Medical Sciences  ·  Area of research: Pharmaacy

DOI: https://doi.org/10.64388/IREV9I11-1717614

Abstract

Inflammatory Bowel Disease (IBD) is a chronic inflammatory disorder affecting the gastrointestinal tract, primarily including Crohn’s disease and Ulcerative colitis. The present study aims to formulate and evaluate polyherbal effervescent granules using extracts of Bauhinia variegata and Clitoria ternatea. These plants possess significant anti-inflammatory, antioxidant, and immunomodulatory properties. Effervescent granules were prepared using the wet granulation method and evaluated for physicochemical parameters such as flow properties, effervescence time, pH, and stability. The results indicated that the formulation exhibited good flow properties, rapid effervescence, and acceptable stability. The study concludes that the developed formulation may serve as a promising herbal alternative for managing IBD.

Keywords

Polyherbal Formulation, Effervescent Granules, Kachnar, And Aparajita.

How to cite this paper

Subodh Kumar, Hakim Singh Rajput, Dr. Amresh Gupta "Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 660-663 https://doi.org/10.64388/IREV9I11-1717614
Subodh Kumar, Hakim Singh Rajput, Dr. Amresh Gupta "Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026, doi: https://doi.org/10.64388/IREV9I11-1717614
Subodh Kumar, Hakim Singh Rajput, Dr. Amresh Gupta (2026). Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease. Iconic Research And Engineering Journals, 9(11). doi: https://doi.org/10.64388/IREV9I11-1717614
Subodh Kumar, Hakim Singh Rajput, Dr. Amresh Gupta "Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026. Crossref, https://doi.org/10.64388/IREV9I11-1717614
@article{1717614,
      author = {Subodh Kumar, Hakim Singh Rajput, Dr. Amresh Gupta},
      title = {Formulation And Development of Polyherbal Effervescent Granules for The Treatment of Inflammatory Bowel Disease},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {11},
      pages = {660-663},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1717614.pdf},
      abstract = {Inflammatory Bowel Disease (IBD) is a chronic inflammatory disorder affecting the gastrointestinal tract, primarily including Crohn’s disease and Ulcerative colitis. The present study aims to formulate and evaluate polyherbal effervescent granules using extracts of Bauhinia variegata and Clitoria ternatea. These plants possess significant anti-inflammatory, antioxidant, and immunomodulatory properties. Effervescent granules were prepared using the wet granulation method and evaluated for physicochemical parameters such as flow properties, effervescence time, pH, and stability. The results indicated that the formulation exhibited good flow properties, rapid effervescence, and acceptable stability. The study concludes that the developed formulation may serve as a promising herbal alternative for managing IBD.},
      keywords = {Polyherbal Formulation, Effervescent Granules, Kachnar, And Aparajita.},
      month = {May},
      doi = {https://doi.org/10.64388/IREV9I11-1717614}
  }