Current Volume 9
Formulation And Evaluation of Polyherbal Oral Disintegrating Tablet for The Treatment of Hypertension: A Comprehensive Review
Abstract
Hypertension is a chronic cardiovascular disorder characterized by elevated blood pressure and is considered one of the leading causes of mortality worldwide. Conventional antihypertensive drugs are effective but are often associated with adverse effects such as dizziness, fatigue, electrolyte imbalance, and poor patient compliance. Herbal medicines have gained increasing attention due to their natural origin, safety, and therapeutic efficacy. The present review focuses on the formulation and evaluation of polyherbal oral disintegrating tablets (ODTs) using Terminalia arjuna bark and Withania somnifera root for the management of hypertension. Terminalia arjuna possesses cardioprotective, antioxidant, anti-inflammatory, and antihypertensive properties, while Withania somnifera exhibits adaptogenic, anti-stress, and cardiotonic activities. Oral disintegrating tablets are advantageous because they disintegrate rapidly in saliva without water, improving patient compliance, especially in geriatric patients. This review discusses hypertension, herbal management, phytochemistry, formulation methods, evaluation parameters, mechanisms of action, and future prospects of polyherbal ODTs.
Keywords
Hypertension, Polyherbal formulation, Oral disintegrating tablets (ODTs), Terminalia arjuna, Herbal medicine, Superdisintegrants
Citations
IRE Journals:
Varun Mishra, Hakim Singh Rajput, Dr. Amresh Gupta, Arun Kumar "Formulation And Evaluation of Polyherbal Oral Disintegrating Tablet for The Treatment of Hypertension: A Comprehensive Review" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 1197-1204 https://doi.org/10.64388/IREV9I11-1717728
IEEE:
Varun Mishra, Hakim Singh Rajput, Dr. Amresh Gupta, Arun Kumar
"Formulation And Evaluation of Polyherbal Oral Disintegrating Tablet for The Treatment of Hypertension: A Comprehensive Review" Iconic Research And Engineering Journals, 9(11) https://doi.org/10.64388/IREV9I11-1717728
About IRE Journals
IRE Journals is an open access online journals established with an aim to publish high quality of research work in various diciplines. We have more than 6 years in publications. Over 2500+ papers already published.
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