Current Volume 9
Formulation And Evaluation Process of Polyherbal Mouth Dissolving Tablet for The Treatment of Insomnia Disorder
Abstract
Insomnia is one of the most prevalent sleep disorders characterized by difficulty in initiating or maintaining sleep, leading to impaired daytime functioning and reduced quality of life. Conventional hypnotic drugs such as benzodiazepines and non-benzodiazepines are associated with adverse effects including dependency, tolerance, cognitive impairment, and withdrawal symptoms. Herbal medicines have emerged as safer alternatives because of their natural origin, fewer side effects, and synergistic therapeutic activity. Polyherbal formulations combine multiple medicinal plants to achieve enhanced pharmacological efficacy through synergism. Mouth dissolving tablets (MDTs) are innovative oral dosage forms that disintegrate rapidly in saliva without the need for water, thereby improving patient compliance and rapid onset of action. The present review discusses insomnia disorder, herbal therapies used in its management, principles of polyherbal formulation, preparation methods of mouth dissolving tablets, excipients used, evaluation parameters, advantages, limitations, and future prospects. Herbal ingredients such as Ashwagandha, Tagara, Brahmi, Jatamansi, and Shankhpushpi possess sedative, anxiolytic, and neuroprotective activities that make them suitable candidates for formulation into polyherbal MDTs. The review highlights the importance of natural therapies and advanced drug delivery systems for effective insomnia management.
Keywords
Mouth dissolving tablets (MDTs), Fast dissolving tablets, Herbal medicine, Sleep disorder, Insomnia
Citations
IRE Journals:
Abhishek Yadav, Hakim Singh Rajput, Dr. Amresh Gupta "Formulation And Evaluation Process of Polyherbal Mouth Dissolving Tablet for The Treatment of Insomnia Disorder" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 1210-1216 https://doi.org/10.64388/IREV9I11-1717729
IEEE:
Abhishek Yadav, Hakim Singh Rajput, Dr. Amresh Gupta
"Formulation And Evaluation Process of Polyherbal Mouth Dissolving Tablet for The Treatment of Insomnia Disorder" Iconic Research And Engineering Journals, 9(11) https://doi.org/10.64388/IREV9I11-1717729
About IRE Journals
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