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1718546PublishedVol 9 · Issue 12

Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation

Ayeni, Olayemi Selimot PhD Akeredolu, Adebisi Gabriel PhD

Subject area: Arts, Social Sciences and Humanities  ·  Area of research: Entrepreneurship

DOI: https://doi.org/10.64388/IREV9I12-1718546

Abstract

This study investigated the relationship between strategic decision-making and firm performance in pharmaceutical small and medium-sized enterprises (SMEs) in Southwest Nigeria, focusing on the mediating role of entrepreneurial orientation. It examined how entrepreneurial orientation enhances the effectiveness of decision-making processes in improving performance outcomes. A mixed-methods design was employed, combining quantitative survey data with qualitative insights. Primary data were collected via structured questionnaires administered to owners, managers, and key decision-makers across six states: Ekiti, Lagos, Ogun, Ondo, Osun, and Oyo. The study population comprised 1,510 registered pharmaceutical SMEs operating in manufacturing, distribution, wholesale, and retail segments. Using Yamane’s formula, a sample of 316 firms was determined, with 305 valid responses analyzed. Data were analyzed through descriptive statistics and mediation analysis using PROCESS Macro (Model 4) in SPSS, supported by bootstrapping. Findings revealed that strategic decision-making positively influences entrepreneurial orientation (β = 0.482, p < 0.001), with firms exhibiting higher innovativeness, proactiveness, and risk-taking. Entrepreneurial orientation also significantly improved firm performance (β = 0.515, p < 0.001). Mediation analysis confirmed that entrepreneurial orientation partially mediates the decision-making–performance relationship, with a significant bootstrapped indirect effect (0.248, 95% CI excluding zero). The study concludes that entrepreneurial orientation is a critical mechanism through which structured decision-making enhances firm performance, reinforcing innovation, proactive strategies, and calculated risk-taking as drivers of competitive advantage.

Keywords

Strategic Decision-Making, Entrepreneurial Orientation, Firm Performance, Pharmaceutical SMEs, Mediation Analysis, Southwest Nigeria.

How to cite this paper

Ayeni, Olayemi Selimot PhD, Akeredolu, Adebisi Gabriel PhD "Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation" Iconic Research And Engineering Journals Volume 9 Issue 12 2026 Page 271-292 https://doi.org/10.64388/IREV9I12-1718546
Ayeni, Olayemi Selimot PhD, Akeredolu, Adebisi Gabriel PhD "Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation" Iconic Research And Engineering Journals, vol. 9, no. 12, Jun. 2026, doi: https://doi.org/10.64388/IREV9I12-1718546
Ayeni, Olayemi Selimot PhD, Akeredolu, Adebisi Gabriel PhD (2026). Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation. Iconic Research And Engineering Journals, 9(12). doi: https://doi.org/10.64388/IREV9I12-1718546
Ayeni, Olayemi Selimot PhD, Akeredolu, Adebisi Gabriel PhD "Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation" Iconic Research And Engineering Journals, vol. 9, no. 12, Jun. 2026. Crossref, https://doi.org/10.64388/IREV9I12-1718546
@article{1718546,
      author = {Ayeni, Olayemi Selimot PhD, Akeredolu, Adebisi Gabriel PhD},
      title = {Strategic Decision-Making and Firm Performance in Pharmaceutical Smes: Examining The Mediating Effect of Entrepreneurial Orientation},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {12},
      pages = {271-292},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1718546.pdf},
      abstract = {This study investigated the relationship between strategic decision-making and firm performance in pharmaceutical small and medium-sized enterprises (SMEs) in Southwest Nigeria, focusing on the mediating role of entrepreneurial orientation. It examined how entrepreneurial orientation enhances the effectiveness of decision-making processes in improving performance outcomes. A mixed-methods design was employed, combining quantitative survey data with qualitative insights. Primary data were collected via structured questionnaires administered to owners, managers, and key decision-makers across six states: Ekiti, Lagos, Ogun, Ondo, Osun, and Oyo. The study population comprised 1,510 registered pharmaceutical SMEs operating in manufacturing, distribution, wholesale, and retail segments. Using Yamane’s formula, a sample of 316 firms was determined, with 305 valid responses analyzed. Data were analyzed through descriptive statistics and mediation analysis using PROCESS Macro (Model 4) in SPSS, supported by bootstrapping. Findings revealed that strategic decision-making positively influences entrepreneurial orientation (β = 0.482, p < 0.001), with firms exhibiting higher innovativeness, proactiveness, and risk-taking. Entrepreneurial orientation also significantly improved firm performance (β = 0.515, p < 0.001). Mediation analysis confirmed that entrepreneurial orientation partially mediates the decision-making–performance relationship, with a significant bootstrapped indirect effect (0.248, 95% CI excluding zero). The study concludes that entrepreneurial orientation is a critical mechanism through which structured decision-making enhances firm performance, reinforcing innovation, proactive strategies, and calculated risk-taking as drivers of competitive advantage.},
      keywords = {Strategic Decision-Making, Entrepreneurial Orientation, Firm Performance, Pharmaceutical SMEs, Mediation Analysis, Southwest Nigeria.},
      month = {June},
      doi = {https://doi.org/10.64388/IREV9I12-1718546}
  }