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1719373 Vol 10 · Issue 1 Download Paper

A Nano-Bio-Liquid Formulation Engineered for Adaptability

G. V. R. Mohana Rao

Subject area: Science,Engineering and Technology  ·  Area of research: Nanobiotechnology, Preventive Healthcare

DOI: 10.64388/IREV10I1-1719373

Abstract

This paper presents One Problem One Drop (OPOD) with a primary focus on NNO (Nasal Navel Multi Solution) and explores the physiological significance of the nasal pathway through current understanding of nasal physiology, oxygen transport, parasympathetic nervous system regulation, the vagus nerve and the gut–brain axis. Preliminary user observations related to respiratory comfort, sleep and general well-being are also discussed as exploratory findings. The paper proposes that supporting healthy nasal physiology represents a promising preventive and curative approach and highlights the need for further studies and controlled clinical investigations to evaluate the role of NNO within the broader OPOD framework.

Keywords

OPOD, Nasal Navel Multi Solution (NNO), Nasal Physiology, Oxygen Transport, Cellular Oxygenation, Vagus Nerve, Parasympathetic Nervous System, Gut–Brain Axis, Respiratory Health, Preventive Health, Homeostasis, Cellular Metabolism.

References

[1] Team QAE-SS Pitch Deck - https://drive.google.com/file/d/1NLIf4smBl8B0sSH_9vanaBF3xGiAQkXU/view?usp=sharing

[2] Prototype Image - https://drive.google.com/file/d/1GMKIcSjZw8EFJKTGtoJhne6EnjxL5LRH/view?usp=sharing

[3] OPOD Demo - https://drive.google.com/file/d/1hJE-TbtOlCyn14B9lBpXhbYyIC3OLakL/view?usp=sharing

[4] OPOD Feedback - https://drive.google.com/file/d/1vS16Z4ISsZQzpSKcfwCHlk7UCcI6t4dW/view?usp=sharing

[5] WHO Global Air Quality Guidelines (2021)

[6] https://www.who.int/publications/i/item/9789240034228

[7] State of Global Air Report

[8] https://www.stateofglobalair.org/

[9] WHO – Air Pollution

[10] https://www.who.int/health-topics/air-pollution

[11] The Lancet Planetary Health

[12] https://www.thelancet.com/journals/lanplh/home

[13] Lancet Countdown on Health and Climate Change

[14] https://www.lancetcountdown.org/

[15] UNEP – Air Pollution

[16] https://www.unep.org/explore-topics/air

[17] American Journal of Rhinology & Allergy

[18] https://journals.sagepub.com/home/ajr

[19] PubMed – Nasal Physiology

[20] https://pubmed.ncbi.nlm.nih.gov/?term=nasal+physiology

[21] C. NITRIC OXIDE & NASAL BREATHING

[22] Lundberg JO et al.

[23] "Nitric oxide in the paranasal sinuses." https://pubmed.ncbi.nlm.nih.gov/?term=nitric+oxide+paranasal+sinuses

[24] PubMed – Nasal Nitric Oxide

[25] https://pubmed.ncbi.nlm.nih.gov/?term=nasal+nitric+oxide

[26] The Journal of Physiology

[27] https://physoc.onlinelibrary.wiley.com/journal/14697793

[28] PubMed – Oxygen Transport

[29] https://pubmed.ncbi.nlm.nih.gov/?term=oxygen+transport

[30] Nature Reviews Molecular Cell Biology

[31] https://www.nature.com/nrm/

[32] PubMed – Oxidative Phosphorylation

[33] https://pubmed.ncbi.nlm.nih.gov/?term=oxidative+phosphorylation

[34] PubMed – ATP Production

[35] https://pubmed.ncbi.nlm.nih.gov/?term=ATP+production

[36] PubMed – Vagus Nerve

[37] https://pubmed.ncbi.nlm.nih.gov/?term=vagus+nerve

[38] PubMed – Parasympathetic Nervous System

[39] https://pubmed.ncbi.nlm.nih.gov/?term=parasympathetic+nervous+system

[40] PubMed – Gut Brain Axis

[41] https://pubmed.ncbi.nlm.nih.gov/?term=gut+brain+axis

[42] PubMed – Microbiome & Brain

[43] https://pubmed.ncbi.nlm.nih.gov/?term=microbiome+brain

[44] PubMed – Nasal Breathing Sleep

[45] https://pubmed.ncbi.nlm.nih.gov/?term=nasal+breathing+sleep

[46] PubMed – Sleep Apnea

[47] https://pubmed.ncbi.nlm.nih.gov/?term=sleep+apnea

[48] PREVENTIVE MEDICINE & SYSTEMS BIOLOGY

[49] New England Journal of Medicine

[50] https://www.nejm.org/

[51] PubMed – Preventive Medicine

[52] https://pubmed.ncbi.nlm.nih.gov/?term=preventive+medicine

How to cite this paper

G. V. R. Mohana Rao "A Nano-Bio-Liquid Formulation Engineered for Adaptability" Iconic Research And Engineering Journals Volume 10 Issue 1 2026 Page 26-35 https://doi.org/10.64388/IREV10I1-1719373
G. V. R. Mohana Rao "A Nano-Bio-Liquid Formulation Engineered for Adaptability" Iconic Research And Engineering Journals, vol. 10, no. 1, Jul. 2026, doi: https://doi.org/10.64388/IREV10I1-1719373
G. V. R. Mohana Rao (2026). A Nano-Bio-Liquid Formulation Engineered for Adaptability. Iconic Research And Engineering Journals, 10(1). doi: https://doi.org/10.64388/IREV10I1-1719373
G. V. R. Mohana Rao "A Nano-Bio-Liquid Formulation Engineered for Adaptability" Iconic Research And Engineering Journals, vol. 10, no. 1, Jul. 2026. Crossref, https://doi.org/10.64388/IREV10I1-1719373
@article{1719373,
      author = {G. V. R. Mohana Rao},
      title = {A Nano-Bio-Liquid Formulation Engineered for Adaptability},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {10},
      number = {1},
      pages = {26-35},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1719373.pdf},
      abstract = {This paper presents One Problem One Drop (OPOD) with a primary focus on NNO (Nasal Navel Multi Solution) and explores the physiological significance of the nasal pathway through current understanding of nasal physiology, oxygen transport, parasympathetic nervous system regulation, the vagus nerve and the gut–brain axis. Preliminary user observations related to respiratory comfort, sleep and general well-being are also discussed as exploratory findings. The paper proposes that supporting healthy nasal physiology represents a promising preventive and curative approach and highlights the need for further studies and controlled clinical investigations to evaluate the role of NNO within the broader OPOD framework.},
      keywords = {OPOD, Nasal Navel Multi Solution (NNO), Nasal Physiology, Oxygen Transport, Cellular Oxygenation, Vagus Nerve, Parasympathetic Nervous System, Gut–Brain Axis, Respiratory Health, Preventive Health, Homeostasis, Cellular Metabolism.},
      month = {July},
      doi = {https://doi.org/10.64388/IREV10I1-1719373}
  }