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1722462 Vol 10 · Issue 2 Download Paper

Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol

S. V. Jadhav

Subject area: Science,Engineering and Technology  ·  Area of research: Dyes Synthesis

DOI: https://doi.org/10.64388/IREV10I2-1722462

Abstract

This study reports the synthesis, Characterization and application of new azo-linked compound, Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl]diazenyl}quinolin-8-ol, for textile applications. The compound was synthesized via diazotization and coupling reactions, with its structure confirmed by FT-IR, 1H-NMR, and 13 C-NMR spectroscopy, The dyes fastness properties were assessed on Terrycloth, nylon, and Cotton Mesh under different conditions: neutral, alkaline (NaOH, and acidic (HCl)environments, Terrycloth exhibited excellent fastness properties across all tests, with minimal color fading. Nylon showed moderate resistance in neutral and acidic environments but was less stable under alkaline conditions. Cotton Mesh the lowest fastness, particularly under alkaline conditions, due to its cellulose-based structure, making it more prone to dye leaching. These results indicate the suitability of Terrycloth and Nylon for high-performance textile applications requiring color durability.

Keywords

Thiadiazole, Azo-dyes, Textile application, Heterocyclic compound.

References

[1] Dhuha Kazem Slman, A.K., Hind A.Sutar, Zahraa Alsaady and Asmaa ali Jawad, Heterocyclic Compounds: AStudy of its Biological Activity. AI-Nahrain Journal of Science. December 2024. ANJS, Vol.27 (5), pp.19-24

[2] Josef Jampilek, Heterocycles in Medicinal Chemistry, Molecules Journals, Oct 2019, 24(21):3839.

[3] 3.Ivana Pibri, Recent Advances: Heterocycles in Drugs and Drug Discovery,International Journal of Molecular Sciences,Aug 2024, 25(17):9503.

[4] 4.Harish Chowhan, Human Health and Dyes for Textiles. Journal of Textile Science & Engineering, 2024. 14(4): p.1-2.

[5] 5.Nadia G. Kandile & Abir S. Na sr, Poly(Vinyl alcohol) membranes-inspired heterocyclic compounds for different applications: and characterization, Spriger Nature, March 2022, Volume 80, pages2367- 2387.

[6] 6.Nikhil Sidhu, Pragati Jain, Chandrima Mukharjee and Praveena Sarpachira Pratheep: Recent advancements in heterocyclic coumpounds as agrochemicals -A Review,Indian Journal of Heterocyclic Chemistry,Apr-2025, Vol-35, pp-443-450.

[7] 7.Tomasz Kosmalski, Renata Kolodiejska:The application of Green solvent in the synthesis of S-Heterocyclic compounds,:International Journals of Mol. Science :2024, 25(17), pp- 9474

[8] 8.Weipeng Sun, Yobei Adachi: Synthesis of heterocyclic thiadiazole condensed germoles with enhanced electron - deficientproperties:Journals of Dyes and Pigments:Jully 2022, Volume 203.

[9] 9. Jiaajiao Guo, Zhouling Xie,: Thiadiazole- based analogues as potential antibacterial agents against methicillin- resistant Staphylococcus aureus( MRSA) and their SAR elucidation: European journals of medicinal Chemistry: Nov-2023, Vol-259, Article-5689.

[10] 10. Shui-Lin Yan, Ming-Yan Yang, Zhao-Hhi Sun, Li-jing Min: Synthesis and Antifungal Activity of 1,2,3-thiadiazole derivatives containing 1,3,4-thiadiazole Moiety:Drug Design & Discovery: Aug 2014, 11(7), pp- 940-943.

[11] 11. C.R.Santhosh, Sampath Chinnam : Recent Progress on anticancer activity of thiadiazoles: A Review: Journals of Result in Chemistry, Nov.2024, 13(2025), 101939.

[12] 12.Vaibhav Saxena: Synthesis and analgesic, antiinflammetry activities of some novel thiadiazole derivatives:International Journals of Pharmaceutical Sciences and Drug Research, 2021, Vol. 13, issue-1.

How to cite this paper

S. V. Jadhav "Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol" Iconic Research And Engineering Journals Volume 10 Issue 2 2026 Page 2312-2318 https://doi.org/10.64388/IREV10I2-1722462
S. V. Jadhav "Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol" Iconic Research And Engineering Journals, vol. 10, no. 2, Aug. 2026, doi: https://doi.org/10.64388/IREV10I2-1722462
S. V. Jadhav (2026). Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol. Iconic Research And Engineering Journals, 10(2). doi: https://doi.org/10.64388/IREV10I2-1722462
S. V. Jadhav "Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol" Iconic Research And Engineering Journals, vol. 10, no. 2, Aug. 2026. Crossref, https://doi.org/10.64388/IREV10I2-1722462
@article{1722462,
      author = {S. V. Jadhav},
      title = {Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl] diazenyl} quinolin-8-ol},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {10},
      number = {2},
      pages = {2312-2318},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1722462.pdf},
      abstract = {This study reports the synthesis, Characterization and application of new azo-linked compound, Synthesis and Characterization of 5-{[5-(2-aminophenyl)-1,3,4-thiadiazol-2-yl]diazenyl}quinolin-8-ol, for textile applications. The compound was synthesized via diazotization and coupling reactions, with its structure confirmed by FT-IR, 1H-NMR, and 13 C-NMR spectroscopy, The dyes fastness properties were assessed on Terrycloth, nylon, and Cotton Mesh under different conditions: neutral, alkaline (NaOH, and acidic (HCl)environments, Terrycloth exhibited excellent fastness properties across all tests, with minimal color fading. Nylon showed moderate resistance in neutral and acidic environments but was less stable under alkaline conditions. Cotton Mesh the lowest fastness, particularly under alkaline conditions, due to its cellulose-based structure, making it more prone to dye leaching. These results indicate the suitability of Terrycloth and Nylon for high-performance textile applications requiring color durability. },
      keywords = {Thiadiazole, Azo-dyes, Textile application, Heterocyclic compound.},
      month = {August},
      doi = {https://doi.org/10.64388/IREV10I2-1722462}
  }