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Comparison Of Macular Thickness Among Myopes and Emmetropes in Port Harcourt, Rivers State, Using Spectral Domain Optical Coherence Tomography
Subject area: Biological & Medical Sciences · Area of research: Vision Science
Abstract
Myopia is a leading cause of visual impairment worldwide and is associated with structural alterations of the retina particularly the macula. Spectral Domain Optical Coherence Tomography (SD-OCT) provides accurate and reproducible measurements of macular thickness, but data among Nigerian adults remain limited. This study comparted macular thickness among myopic and emmetropic adults in Port Harcourt, Rivers State, using SD-OCT. A comparative cross-sectional study was conducted among adults aged 18-40 years attending an eye specialist hospital. Participants were classified into myopic and emmetropic groups according to spherical equivalent refractive error. Central, inner, outer, and average ocular thicknesses were measured using a Topcon SD-OCT system based on the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol. Data were analyzed using SPSS version 23, with statistical significance set at p<0.05. Myopic eyes had significantly lower macular thickness than emmetropic eyes. Central macular thickness was 188.11 ± 24.83 µm in myopes versus 200.30 ± 16.81 µm in emmetropes (p = 0.046). Inner macular thickness was 281.75 ± 14.44 µm versus 295.92 ± 44.76 µm (p = 0.039), outer macular thickness was 257.80 ± 13.90 µm versus 280.07 ± 9.30 µm (p < 0.001), while average macular thickness was 266.99 ± 12.78 µm versus 291.66 ± 19.02 µm (p < 0.001). Myopic eyes demonstrated significantly reduced central, inner, outer, and average macular thickness compared with emmetropic eyes. These findings emphasize the importance of considering refractive status during SD-OCT interpretation and support further studies involving larger Nigerian populations.
Keywords
Myopia; Emmetropia; Macular Thickness; Optical Coherence Tomography; SD-OCT.
How to cite this paper
@article{1722614,
author = {Ozurumba Oluchi Adanna, Azuamah Y. C., Daniel-Nwosu E. I., Megwas A. U.; Ikoro N. C., Sam-Duru P. A.; Nwannesindu U. E.; Eronini Y. R.},
title = {Comparison Of Macular Thickness Among Myopes and Emmetropes in Port Harcourt, Rivers State, Using Spectral Domain Optical Coherence Tomography},
journal = {Iconic Research And Engineering Journals},
year = {2026},
volume = {10},
number = {2},
pages = {3257-3264},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1722614.pdf},
abstract = {Myopia is a leading cause of visual impairment worldwide and is associated with structural alterations of the retina particularly the macula. Spectral Domain Optical Coherence Tomography (SD-OCT) provides accurate and reproducible measurements of macular thickness, but data among Nigerian adults remain limited. This study comparted macular thickness among myopic and emmetropic adults in Port Harcourt, Rivers State, using SD-OCT. A comparative cross-sectional study was conducted among adults aged 18-40 years attending an eye specialist hospital. Participants were classified into myopic and emmetropic groups according to spherical equivalent refractive error. Central, inner, outer, and average ocular thicknesses were measured using a Topcon SD-OCT system based on the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol. Data were analyzed using SPSS version 23, with statistical significance set at p<0.05. Myopic eyes had significantly lower macular thickness than emmetropic eyes. Central macular thickness was 188.11 ± 24.83 µm in myopes versus 200.30 ± 16.81 µm in emmetropes (p = 0.046). Inner macular thickness was 281.75 ± 14.44 µm versus 295.92 ± 44.76 µm (p = 0.039), outer macular thickness was 257.80 ± 13.90 µm versus 280.07 ± 9.30 µm (p < 0.001), while average macular thickness was 266.99 ± 12.78 µm versus 291.66 ± 19.02 µm (p < 0.001). Myopic eyes demonstrated significantly reduced central, inner, outer, and average macular thickness compared with emmetropic eyes. These findings emphasize the importance of considering refractive status during SD-OCT interpretation and support further studies involving larger Nigerian populations.},
keywords = {Myopia; Emmetropia; Macular Thickness; Optical Coherence Tomography; SD-OCT.},
month = {August},
}