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From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria

Dr. Adeniyi Olusegun Oyeyemi Muriana Olotu Ayodele Shola Alegbeleye Henrietta Adeniyi Timileyin Joshua Oluwadepo Abiodun Adegoke Oluwabunmi Ibitoye Kester Ogboli-Peters

Subject area: Biological & Medical Sciences  ·  Area of research: Childhood Tuberculosis, Public Health Epidemiology

Abstract

Background: Childhood tuberculosis (TB) remains under-recognized in many settings because children can present with nonspecific symptoms, microbiological confirmation is often difficult, and health systems may rely heavily on passive presentation. Routine TB notification data can provide an important signal of programme performance, but changes in notifications must be interpreted carefully because they may reflect changes in disease burden, case finding, diagnosis, reporting or several factors simultaneously. Objective: To describe five-quarter trends in childhood TB notification in Ekiti State, Nigeria, and to interpret changes in childhood TB notifications and age distribution within the context of documented programme strengthening activities. Methods: This descriptive programme-based analysis used validated Ekiti State DHIS2/HMIS data presented in the September 2026 Childhood TB Update. Data included total TB notifications, childhood TB notifications and the percentage of childhood TB among all notified TB cases for Q2 2025 through Q2 2026. Age-specific childhood TB counts were available for Q1 and Q2 2026. Programme information on training and mentorship, integration of childhood TB screening into primary health care, strengthened contact investigation, improved access to chest X-ray and molecular testing, improved specimen referral, HIV and nutrition collaboration, and LGA monitoring was considered in interpreting the trends. Descriptive counts, proportions and absolute changes were examined. Results: Childhood TB notifications were 7, 4, 16, 9 and 20 cases across Q2 2025, Q3 2025, Q4 2025, Q1 2026 and Q2 2026, respectively. Childhood TB represented 3%, 2%, 6%, 4% and 7% of all notified TB cases in the corresponding quarters. Q2 2026 had both the highest childhood TB count and the highest childhood TB proportion in the five-quarter series. Total TB notifications also reached their highest level in Q2 2026, at 302 cases. From Q1 to Q2 2026, notifications among children aged 0–4 years increased from 4 to 12 cases, while notifications among children aged 5–14 years increased from 5 to 8 cases. Conclusion: The Ekiti notification curve changed substantially over the five quarters, with childhood TB increasing from 3% of all notified TB cases in Q2 2025 to 7% in Q2 2026. The increase occurred alongside documented programme strengthening. The findings are therefore consistent with improved detection being an important possible contributor, although the available data cannot establish causality or distinguish improved case finding from changes in underlying disease incidence. Future monitoring should link notification trends to screening coverage, household contact investigation, diagnostic access, referral completion and preventive treatment outcomes.

Keywords

childhood tuberculosis; TB notification; case finding; routine health information system; DHIS2; HMIS; Nigeria; children under five; programme performance; Ekiti State.

References

[1] World Health Organization. Global tuberculosis report 2025. Geneva: World Health Organization; 2025. WHO

[2] World Health Organization. WHO consolidated guidelines on tuberculosis. Module 5: management of tuberculosis in children and adolescents. Geneva: World Health Organization; 2022. WHO

[3] World Health Organization. WHO operational handbook on tuberculosis. Module 5: management of tuberculosis in children and adolescents. Geneva: World Health Organization; 2022. WHO

[4] World Health Organization. WHO consolidated guidelines on tuberculosis. Module 1: prevention – tuberculosis preventive treatment. 2nd ed. Geneva: World Health Organization; 2024. WHO

[5] World Health Organization. WHO operational handbook on tuberculosis. Module 1: prevention – tuberculosis preventive treatment. 2nd ed. Geneva: World Health Organization; 2024. WHO

[6] World Health Organization. WHO consolidated guidelines on tuberculosis. Module 3: diagnosis – rapid diagnostics for tuberculosis detection. Geneva: World Health Organization; current edition. WHO

[7] World Health Organization. WHO consolidated guidelines on tuberculosis. Module 4: treatment and care. Geneva: World Health Organization; current edition. WHO

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[9] World Health Organization. Implementing the End TB Strategy: the essentials. Geneva: World Health Organization. WHO

[10] Stop TB Partnership. The Global Plan to End TB 2023–2030. Geneva: Stop TB Partnership; 2022.

[11] Federal Ministry of Health, Nigeria. National Tuberculosis, Leprosy and Buruli Ulcer Control Programme. National guidelines for tuberculosis prevention, diagnosis, treatment and control. Abuja: Federal Ministry of Health.

[12] Schwoebel V, Koura KG, Adjobimey M, et al. Tuberculosis contact investigation and preventive therapy among young children in Africa. Int J Tuberc Lung Dis. 2020.

[13] Martinez L, Shen Y, Mupere E, et al. Transmission of Mycobacterium tuberculosis in households and risk of tuberculosis disease among children. Published epidemiological evidence.

[14] Reider HL, et al. Yield of source-case and contact investigations in identifying previously undiagnosed childhood tuberculosis. Published evidence.

[15] Effectiveness of a community-based approach for the investigation and management of children with household tuberculosis contact in Cameroon and Uganda: a cluster-randomised trial. Published trial evidence. PubMed

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[18] Ekiti State TB/Leprosy/Buruli Ulcer Control Programme. Childhood Tuberculosis Update: Progress, Gaps, Challenges and Priority Actions. Validated DHIS2/HMIS programme data. September 2026.

How to cite this paper

Dr. Adeniyi Olusegun Oyeyemi, Muriana Olotu, Ayodele Shola Alegbeleye; Henrietta Adeniyi, Timileyin Joshua Oluwadepo; Abiodun Adegoke, Oluwabunmi Ibitoye; Kester Ogboli-Peters "From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria" Iconic Research And Engineering Journals Volume 10 Issue 3 2026 Page 2217-2228
Dr. Adeniyi Olusegun Oyeyemi, Muriana Olotu, Ayodele Shola Alegbeleye; Henrietta Adeniyi, Timileyin Joshua Oluwadepo; Abiodun Adegoke, Oluwabunmi Ibitoye; Kester Ogboli-Peters "From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria" Iconic Research And Engineering Journals, vol. 10, no. 3, Sep. 2026
Dr. Adeniyi Olusegun Oyeyemi, Muriana Olotu, Ayodele Shola Alegbeleye; Henrietta Adeniyi, Timileyin Joshua Oluwadepo; Abiodun Adegoke, Oluwabunmi Ibitoye; Kester Ogboli-Peters (2026). From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria. Iconic Research And Engineering Journals, 10(3).
Dr. Adeniyi Olusegun Oyeyemi, Muriana Olotu, Ayodele Shola Alegbeleye; Henrietta Adeniyi, Timileyin Joshua Oluwadepo; Abiodun Adegoke, Oluwabunmi Ibitoye; Kester Ogboli-Peters "From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria" Iconic Research And Engineering Journals, vol. 10, no. 3, Sep. 2026.
@article{1723203,
      author = {Dr. Adeniyi Olusegun Oyeyemi, Muriana Olotu, Ayodele Shola Alegbeleye; Henrietta Adeniyi, Timileyin Joshua Oluwadepo; Abiodun Adegoke, Oluwabunmi Ibitoye; Kester Ogboli-Peters},
      title = {From 3% TO 7% Five-Quarter Trends in Childhood Tuberculosis Notification and Case Finding in Ekiti State, Nigeria},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {10},
      number = {3},
      pages = {2217-2228},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1723203.pdf},
      abstract = {Background: Childhood tuberculosis (TB) remains under-recognized in many settings because children can present with nonspecific symptoms, microbiological confirmation is often difficult, and health systems may rely heavily on passive presentation. Routine TB notification data can provide an important signal of programme performance, but changes in notifications must be interpreted carefully because they may reflect changes in disease burden, case finding, diagnosis, reporting or several factors simultaneously.

Objective: To describe five-quarter trends in childhood TB notification in Ekiti State, Nigeria, and to interpret changes in childhood TB notifications and age distribution within the context of documented programme strengthening activities.

Methods: This descriptive programme-based analysis used validated Ekiti State DHIS2/HMIS data presented in the September 2026 Childhood TB Update. Data included total TB notifications, childhood TB notifications and the percentage of childhood TB among all notified TB cases for Q2 2025 through Q2 2026. Age-specific childhood TB counts were available for Q1 and Q2 2026. Programme information on training and mentorship, integration of childhood TB screening into primary health care, strengthened contact investigation, improved access to chest X-ray and molecular testing, improved specimen referral, HIV and nutrition collaboration, and LGA monitoring was considered in interpreting the trends. Descriptive counts, proportions and absolute changes were examined.

Results: Childhood TB notifications were 7, 4, 16, 9 and 20 cases across Q2 2025, Q3 2025, Q4 2025, Q1 2026 and Q2 2026, respectively. Childhood TB represented 3%, 2%, 6%, 4% and 7% of all notified TB cases in the corresponding quarters. Q2 2026 had both the highest childhood TB count and the highest childhood TB proportion in the five-quarter series. Total TB notifications also reached their highest level in Q2 2026, at 302 cases. From Q1 to Q2 2026, notifications among children aged 0–4 years increased from 4 to 12 cases, while notifications among children aged 5–14 years increased from 5 to 8 cases.

Conclusion: The Ekiti notification curve changed substantially over the five quarters, with childhood TB increasing from 3% of all notified TB cases in Q2 2025 to 7% in Q2 2026. The increase occurred alongside documented programme strengthening. The findings are therefore consistent with improved detection being an important possible contributor, although the available data cannot establish causality or distinguish improved case finding from changes in underlying disease incidence. Future monitoring should link notification trends to screening coverage, household contact investigation, diagnostic access, referral completion and preventive treatment outcomes.},
      keywords = {childhood tuberculosis; TB notification; case finding; routine health information system; DHIS2; HMIS; Nigeria; children under five; programme performance; Ekiti State.},
      month = {September},
  }