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Ceftriaxone Adverse Events and its Extraction from Body Fluids: Review
Subject area: Science,Engineering and Technology · Area of research: Forensic Toxicology
Abstract
Ceftriaxone also called ceftriaxone/Rocephin third-generation cephalosporin mainly works against bacterial infection in the human body. Ceftriaxone is a beta-lactam stable antibiotic drug that mainly works on the principle of cell destruction cell using inhibition of peptidoglycan synthesis. Ceftriaxone works against both gram-positive and gram-negative classes of bacterial infections such as infections caused by prevotella, streptococcus, and E. coli. There are some known adverse effects but in rare cases, those are seen in a very aggressive manner. Forensically such drug extraction is crucial for purpose of toxicological and chemical analysis from body fluids found on the scene of the crime. Different types of extraction processes are used for drugs from body fluids such as SPE-GC, and SPE-MS/ HPLC.
Keywords
Cephalosporin, E. coli, Gram-positive bacteria, SPE-GC (Solid Phase Extraction-Gas Chromatography
References
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How to cite this paper
@article{1704113,
author = {Sarang S. Damle, Manjushri S. Bagul},
title = {Ceftriaxone Adverse Events and its Extraction from Body Fluids: Review},
journal = {Iconic Research And Engineering Journals},
year = {2023},
volume = {6},
number = {8},
pages = {156-160},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1704113.pdf},
abstract = {Ceftriaxone also called ceftriaxone/Rocephin third-generation cephalosporin mainly works against bacterial infection in the human body. Ceftriaxone is a beta-lactam stable antibiotic drug that mainly works on the principle of cell destruction cell using inhibition of peptidoglycan synthesis. Ceftriaxone works against both gram-positive and gram-negative classes of bacterial infections such as infections caused by prevotella, streptococcus, and E. coli. There are some known adverse effects but in rare cases, those are seen in a very aggressive manner. Forensically such drug extraction is crucial for purpose of toxicological and chemical analysis from body fluids found on the scene of the crime. Different types of extraction processes are used for drugs from body fluids such as SPE-GC, and SPE-MS/ HPLC.},
keywords = {Cephalosporin, E. coli, Gram-positive bacteria, SPE-GC (Solid Phase Extraction-Gas Chromatography},
month = {February},
}