Ceftriaxone Adverse Events and its Extraction from Body Fluids: Review

• Author(s): Sarang S. Damle ; Manjushri S. Bagul
• Paper ID: 1704113
• Page: 156-160
• Published Date: 24-02-2023
• Published In: Iconic Research And Engineering Journals
• Publisher: IRE Journals
• e-ISSN: 2456-8880
• Volume/Issue: Volume 6 Issue 8 February-2023

Abstract

Ceftriaxone also called ceftriaxone/Rocephin third-generation cephalosporin mainly works against bacterial infection in the human body. Ceftriaxone is a beta-lactam stable antibiotic drug that mainly works on the principle of cell destruction cell using inhibition of peptidoglycan synthesis. Ceftriaxone works against both gram-positive and gram-negative classes of bacterial infections such as infections caused by prevotella, streptococcus, and E. coli. There are some known adverse effects but in rare cases, those are seen in a very aggressive manner. Forensically such drug extraction is crucial for purpose of toxicological and chemical analysis from body fluids found on the scene of the crime. Different types of extraction processes are used for drugs from body fluids such as SPE-GC, and SPE-MS/ HPLC.

Keywords

Cephalosporin, E. coli, Gram-positive bacteria, SPE-GC (Solid Phase Extraction-Gas Chromatography

Citations

IRE Journals:
Sarang S. Damle , Manjushri S. Bagul "Ceftriaxone Adverse Events and its Extraction from Body Fluids: Review" Iconic Research And Engineering Journals Volume 6 Issue 8 2023 Page 156-160

IEEE:
Sarang S. Damle , Manjushri S. Bagul "Ceftriaxone Adverse Events and its Extraction from Body Fluids: Review" Iconic Research And Engineering Journals, 6(8)