International Peer-Reviewed Journal•Open Access•ISSN 2456-8880
irejournals@gmail.com•+91-7433024337

Home / Current Issue / Paper 1704847

1704847 Vol 7 · Issue 1 Download Paper

Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted

Mei-Lee Hwang Rong-Luh Jeng Pei-Hsuan Tsai Jyh-Ferng Yang

Subject area: Biological & Medical Sciences  ·  Area of research: Plant Biochemistry

Abstract

This study aimed to investigate, the chemical composition of acetone leaf extracts of Chromolaen aodorata (L.) was analysed by gas chromatography-mass spectrometry (GC-MS). A total of 53 chemical compounds were recognized, accounting for 37.36% of the composition of the acetone extracts. The three major components are Germacrene D (5.73%), 5,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one (3.33%) and Phytol (2.90%).

Keywords

Chromolaenaodorata, Germacrene D, 5,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one, Phytol, Gaschromatography-mass spectrometry

References

[1] V. Shilpa, M.Rupesh Kumar, H. S. Harshitha, H. B. Chinthana, and B. Ramesh, Pharmacological and Phytochemical Evaluation of Chromolaena Odorata,‖ Int. j. pharm. drug. anal., vol. 8, no. 6, pp. 1-5, July 2020.

[2] A.G. Omokhua-Uyi, M.A. Abdalla, C.M. Leonard, A. Aro, O.O. Uyi, J. Van Staden, and L.J. McGaw, Flavonoids isolated from the South African weed Chromolaena odorata (Asteraceae) have pharmacological activity against uropathogens,‖ BMC Complement. Med. Ther., vol. 20, pp. 1-15, July 2020.

[3] F. Olawalea, K. Olofinsanc, and O. Iwaloye, Biological activities of Chromolaena odorata: A mechanistic review,‖ South African Journal of Botany, vol. 144, pp. 44-57, Sep. 2021.

[4] V. Kanase, and S. Shaikh, A Pharmacognostic And Pharmacological Review On Chromolaena odorata (siam weed),‖ Asian J Pharm Clin Res, vol. 11, no 10, pp. 34-38, May 2018.

[5] M. Yolmeh, M. B. Habibi Najafi, and R. Farhoosh, Optimisation of ultrasound-assisted extraction of natural pigment from annatto seeds by response surface methodology (RSM),‖ Food Chemistry, vol. 155, pp. 319-324, 2014.

[6] J. Quintero Quiroz, A.M.N. Duran, M.S. Garcia, G.L.C. Gomez, and J.J.R. Camargo, Ultrasound- assisted extraction of bioactive compounds from annatto seeds, evaluation of their antimicrobial and antioxidant activity, and identification of main compounds by LC/ESI-MS analysis, Int. J. Food Sci.,‖ vol. 2019, pp. 1-9, July 2019.

[7] M. Atindehou, L. Lagnika, B. Guérold, JeanMarc Strub, J.M. Zhao, M. Dorsselaer, A.V. Marchioni, E. Prévost, G. Haikel, Y. Taddéi, C. Sanni, and M. A. Metz -Boutigue, Isolation and identification of two anti-bacterial agents from Chromolaena odorata L. active against four diarrheal strains,‖ Adv. Microbiol., vol. 3, pp. 115-121, 2013.

[8] V.B. Raman, L.A. Samuel, P.M. Saradhi, N.B. Rao, N.A. VamsiKrishna, M. Sudhakar, and T.M. Radhakrishnan, Anti-bacterial, antioxidant activity and GC-MS analysis of Eupatorium odoratum,‖ Asian J.Pharmacol.Clin.Res., vol. 5, pp. 99-106, 2012.

[9] G.N. Anyasor, D.A. Aina, M. Olushola, and A.F. Aniyikawe, Phytochemical constituents, proximate analysis, antioxidants, anti-bacterial and wound healing properties of leaf extracts of Chromolaena odorata,‖ Ann. Biol. Res., vol. 2, pp. 441-451, 2011.

[10] K. Vijayaraghavan, M.S. Ali, and R. Maruthi, Studies on phytochemical screening and antioxidant activity of Chromolaena odorata and Annona squamosa,‖ Int. J. Innov. Res. Sci. Eng. Technol., vol. 2, pp. 7315-7321, 2013.

[11] J. Liu, C. Chen, X. Wan, G. Yao, S. Bao, F. Wang, K. Wang, T. Song, P. Han, and H. Jiang, Identification of the sesquiterpene synthase AcTPS1 and high production of (–)-germacrene D in metabolically engineered Saccharomyces cerevisiae,‖ Microb Cell Fact, vol. 21, pp. 89- 10, May 2022.

[12] N. Bülow, and W. A. König, The role of germacrene D as a precursor in sesquiterpene biosynthesis: investigation of acid catalyzed, photochemically and thermally induced rearrangements,‖ Phytochemistry, vol. 55, pp. 141-168, Sep. 2000.

[13] P. Steliopoulos, M. Wüst, K. P. Adam, and A. Mosandl, Biosynthesis of the sesquiterpene germacrene D in Solidago canadensis: 13 C and (2) H labeling studies,‖ Phytochemistry, vol. 60, no. 1, pp. 13-20, May 2002.

[14] S. Casiglia, M. Bruno, M. Bramucci, L. Quassinti, G. Lupidi, D. Fiorini, and F. Maggi, Kundmannia sicula (L.) DC: a rich source of germacrene D,‖ Journal of Essential Oil Research, vol. 29, no. 6, pp. 437–442, Jun. 2017.

[15] H. Pandith, X. Zhang, S. Thongpraditchote, Y. Wongkrajang, W. Gritsanapan, and S. J. Baek, Effect of Siam weed extract and its bioactive component scutellarein tetramethyl ether on anti- inflammatory activity through NF-κB pathway,‖ Journal of Ethnopharmacology, vol. 147, no. 2, pp.434–441, May 2013.

[16] C.M. Claro-Cala, E. Grao-Cruces, R. Toscano, M.C. Millan-Linares, S. Montserrat-dela Paz, M.E. Martin, Acyclic Diterpene Phytol from Hemp Seed Oil (Cannabis sativa L.) Exerts Anti- Inflammatory Activity on Primary Human Monocytes Macrophages,‖ Foods, vol. 11, pp. 2366-2377, Aug. 2022.

How to cite this paper

Mei-Lee Hwang, Rong-Luh Jeng, Pei-Hsuan Tsai, Jyh-Ferng Yang "Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted" Iconic Research And Engineering Journals Volume 7 Issue 1 2023 Page 146-152
Mei-Lee Hwang, Rong-Luh Jeng, Pei-Hsuan Tsai, Jyh-Ferng Yang "Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted" Iconic Research And Engineering Journals, vol. 7, no. 1, Jul. 2023
Mei-Lee Hwang, Rong-Luh Jeng, Pei-Hsuan Tsai, Jyh-Ferng Yang (2023). Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted. Iconic Research And Engineering Journals, 7(1).
Mei-Lee Hwang, Rong-Luh Jeng, Pei-Hsuan Tsai, Jyh-Ferng Yang "Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted" Iconic Research And Engineering Journals, vol. 7, no. 1, Jul. 2023.
@article{1704847,
      author = {Mei-Lee Hwang, Rong-Luh Jeng, Pei-Hsuan Tsai, Jyh-Ferng Yang},
      title = {Gas Chromatographic-Mass Spectrometric Analysis of the Acetone Extract of Chromolaena Odorata (L.) Using Ultrasound-Assisted},
      journal = {Iconic Research And Engineering Journals},
      year = {2023},
      volume = {7},
      number = {1},
      pages = {146-152},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1704847.pdf},
      abstract = {This study aimed to investigate, the chemical composition of acetone leaf extracts of Chromolaen aodorata (L.) was analysed by gas chromatography-mass spectrometry (GC-MS). A total of 53 chemical compounds were recognized, accounting for 37.36% of the composition of the acetone extracts. The three major components are Germacrene D (5.73%), 5,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one (3.33%) and Phytol (2.90%).},
      keywords = {Chromolaenaodorata, Germacrene D, 5,6,7-trimethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one, Phytol, Gaschromatography-mass spectrometry},
      month = {July},
  }