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1705271 Vol 7 · Issue 6 Download Paper

Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review

Anitha W. Sree Janardhanan V.

Subject area: Science,Engineering and Technology  ·  Area of research: Pharmacy

Abstract

The development of novel drug delivery systems has gained considerable attention in recent years due to their potential to enhance the bioavailability and therapeutic efficacy of drugs. One such approach is the formulation of nanoparticle-loaded fast dissolving tablets, which have shown promising results in improving drug release and absorption. In this review article, we will focus on the optimization, formulation, design, and evaluation of nano particle-loaded fast dissolving tablets of Rivaroxaban, ananticoagulant, for bioavailability enhancement. We will discuss the various techniques used for nanoparticle preparation, optimization of formulation parameters, and the evaluation methods employed to assess the performance of these tablets.

Keywords

Rivaroxaban Tablets, Bioavailability, nanoparticle-loaded, anticoagulant

References

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[2] Bhalekar, M. R ., Pokharkar, V. B., & Madgulkar, A. R. (2017). Bioavailability enhancement techniques for poorly soluble drugs. Journal of Pharmaceutical Investigation, 47(2), 111-120.

[3] Chen, X., Wei, M., Wang, X., Wang, Y., & Xu, L. (2016). Preparation and evaluation of nanoparticle loaded fast dissolving tablets for improved drug delivery. International Journal of Pharmaceutics, 513(1-2), 105-114.

[4] Desai, P., & Patel, P. (2017). An overview of optimization techniques for fast dissolving tablets. International Journal of Pharmaceutical Sciences and Research, 8(9), 3503-3515.

[5] Ghimire, N., Pangeni, R., & Pant, K. (2018). Formulation development and optimization of fast dissolving tablet of clopidogrelbisulfate using Response Surface Methodology. Pharmaceutics, 10 (4), 7.

[6] Kamble, B. S., & Dhoble, S. R. (2018). Design and evaluation of fast dissolving tablets of famotidine for enhanced drug delivery. International Journal of Pharmacy and Pharmaceutical Sciences, 10(4), 61-68.

[7] Kumar, S., Dandagi, P., & Mastiholimath, V. (2018). Evaluation of novel formulations of fast dissolving tablets using different natural polymers. Journal of Pharmacology and Clinical Research, 9 (11), 1-7.

[8] Mali, A.V., & Dhawale, S.C. (2019). Development and optimization of fast dissolving tablets of aripiprazole using quality by design approach. Journal of Drug Delivery Science and Technology,54,101317.

[9] Pardeshi, A. B., Belgamwar, V. S. , & Surana, S. J. (2017). Optimized fast dissolving tablets of rizatriptan benzoate: Formulation, evaluation and statistical optimization using Design of Experiment (DoE).

[10] Saudi Pharmaceutical Journal, 25(8), 1181-1192.

[11] Tang, X., Sun, F., Fang, T., Zhang, Z.,& Chen, H.(2019). Enhancedoral bio availability of albendazole through fast dissolving tablets with nanoparticle-loaded solid dispersion. Drug Development and Industrial Pharmacy, 45(10), 1587-1594.

How to cite this paper

Anitha W., Sree Janardhanan V. "Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review" Iconic Research And Engineering Journals Volume 7 Issue 6 2023 Page 108-115
Anitha W., Sree Janardhanan V. "Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review" Iconic Research And Engineering Journals, vol. 7, no. 6, Dec. 2023
Anitha W., Sree Janardhanan V. (2023). Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review. Iconic Research And Engineering Journals, 7(6).
Anitha W., Sree Janardhanan V. "Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review" Iconic Research And Engineering Journals, vol. 7, no. 6, Dec. 2023.
@article{1705271,
      author = {Anitha W., Sree Janardhanan V.},
      title = {Nano-Enhanced Rivaroxaban Tablets: Formulation and Bioavailability - A Review},
      journal = {Iconic Research And Engineering Journals},
      year = {2023},
      volume = {7},
      number = {6},
      pages = {108-115},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1705271.pdf},
      abstract = {The development of novel drug delivery systems has gained considerable attention in recent years due to their potential to enhance the bioavailability and therapeutic efficacy of drugs. One such approach is the formulation of nanoparticle-loaded fast dissolving tablets, which have shown promising results in improving drug release and absorption. In this review article, we will focus on the optimization, formulation, design, and evaluation of nano particle-loaded fast dissolving tablets of Rivaroxaban, ananticoagulant, for bioavailability enhancement. We will discuss the various techniques used for nanoparticle preparation, optimization of formulation parameters, and the evaluation methods employed to assess the performance of these tablets.},
      keywords = {Rivaroxaban Tablets, Bioavailability, nanoparticle-loaded, anticoagulant},
      month = {December},
  }