The Impact of Gut Microbiome On Human Health: A Biochemical Perspective

• Author(s): Bibi Ayesa ; Dr. Mst. Shahinur Begum ; Farheen Iqbal ; Banasree Roy Urmi; Rajib Kumar Malakar ; Sayed Hossain; Md. Jobaer Rahman Rashed
• Paper ID: 1709456
• Page: 809-817
• Published Date: 31-05-2024
• Published In: Iconic Research And Engineering Journals
• Publisher: IRE Journals
• e-ISSN: 2456-8880
• Volume/Issue: Volume 7 Issue 11 May-2024

Abstract

The gut microbiota of humans is essential for maintaining good health because it interacts in many ways with the host. This study explores short-chain fatty acids (SCFAs), their similar metabolic molecules in the gut, and their roles in metabolic, nervous, and immune functions. To find out how wellness markers are linked to certain microbes in your gut, this research tests stool samples and carries out 16S rRNA sequencing and metabolomics. It was found that an increase in butyrate and propionate levels leads to less general inflammation and better blood markers for health. Likewise, other neurotransmitters in microbes, especially gamma-aminobutyric acid (GABA) and serotonin, have been connected to better cognition and improved mood. The findings indicate that gut biochemistry plays a key part in communication between gut and brain or immune systems, offering new approaches for using microbiomes for treatment and diagnosis. According to the research, working with nutrition and the microbiota in different groups can improve overall health results.

Keywords

Gut microbiome; Short-chain fatty acids (SCFAs); Neurotransmitters; Biochemical signaling; Gut-brain axis; Metabolomics; Human health; GABA; Serotonin; Microbial metabolites

Citations

IRE Journals:
Bibi Ayesa , Dr. Mst. Shahinur Begum , Farheen Iqbal , Banasree Roy Urmi; Rajib Kumar Malakar , Sayed Hossain; Md. Jobaer Rahman Rashed "The Impact of Gut Microbiome On Human Health: A Biochemical Perspective" Iconic Research And Engineering Journals Volume 7 Issue 11 2024 Page 809-817

IEEE:
Bibi Ayesa , Dr. Mst. Shahinur Begum , Farheen Iqbal , Banasree Roy Urmi; Rajib Kumar Malakar , Sayed Hossain; Md. Jobaer Rahman Rashed "The Impact of Gut Microbiome On Human Health: A Biochemical Perspective" Iconic Research And Engineering Journals, 7(11)