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Current Trends in Nucleic Acids
Subject area: Biological & Medical Sciences · Area of research: Haematology/Transfusion Science
Abstract
Recent advancements in nucleic acid research have revolutionized our understanding of genetic regulation, diagnostics, and therapeutics. The emergence of next-generation RNA technologies, including RNA-based vaccines and RNA editing tools such as Adenosine Deaminase Acting on RNA (ADAR)-mediated systems, has expanded the utility of nucleic acids beyond traditional gene expression roles. In parallel, Clustered Regularly Interspaced Short Palindomic Repeats (CRISPR)-Cas systems have evolved into more precise, efficient, and programmable platforms for genome and epigenome editing, with innovations like CRISPR-Cas9 enabling nucleic acid detection and RNA manipulation. Moreover, nanopore sequencing and single-molecule real-time sequencing technologies are driving ultra-fast, high-resolution genomic analysis, empowering personalized medicine and microbiome profiling. Collectively, these trends mark a transformative era in nucleic acid research, fostering breakthroughs in precision medicine, synthetic biology, and disease diagnostics.
Keywords
Nucleic acid, Deoxyribonucleic acid, Ribonucleic acid, Therapeutics, Diagnostics, Gene editing, Vaccine, Vectors, Nanoparticles.
How to cite this paper
@article{1710336,
author = {Okereke, Chibueze Aphogu, Prof. Ufelle Silas},
title = {Current Trends in Nucleic Acids},
journal = {Iconic Research And Engineering Journals},
year = {2025},
volume = {9},
number = {2},
pages = {1052-1063},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1710336.pdf},
abstract = {Recent advancements in nucleic acid research have revolutionized our understanding of genetic regulation, diagnostics, and therapeutics. The emergence of next-generation RNA technologies, including RNA-based vaccines and RNA editing tools such as Adenosine Deaminase Acting on RNA (ADAR)-mediated systems, has expanded the utility of nucleic acids beyond traditional gene expression roles. In parallel, Clustered Regularly Interspaced Short Palindomic Repeats (CRISPR)-Cas systems have evolved into more precise, efficient, and programmable platforms for genome and epigenome editing, with innovations like CRISPR-Cas9 enabling nucleic acid detection and RNA manipulation. Moreover, nanopore sequencing and single-molecule real-time sequencing technologies are driving ultra-fast, high-resolution genomic analysis, empowering personalized medicine and microbiome profiling. Collectively, these trends mark a transformative era in nucleic acid research, fostering breakthroughs in precision medicine, synthetic biology, and disease diagnostics. },
keywords = {Nucleic acid, Deoxyribonucleic acid, Ribonucleic acid, Therapeutics, Diagnostics, Gene editing, Vaccine, Vectors, Nanoparticles. },
month = {August},
}