A UV-Correlation Survey of some Local Medicinal Plants use for Treating Malaria to Common Antimalaria Drugs (Quinine, Chloroquine and Halfan)

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@article{1715347,
      author = {Joseph Zekeri Okosun, Clinton Etineh; Victor Ogaga Ololo, Blessed Chukwuemeka Anyanwu; Nwamaka Onyeachonam, Ruth I. Ojombo C Amina Aliyu; Buhari Salamatu B., Farida M. Shehu; Fatima Y. Abdullahi},
      title = {A UV-Correlation Survey of some Local Medicinal Plants use for Treating Malaria to Common Antimalaria Drugs (Quinine, Chloroquine and Halfan)},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {9},
      pages = {3328-3340},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1715347.pdf},
      abstract = {The scientific assessment of traditionally used medicinal herbs has gained increased attention due to the growing resistance of Plasmodium species to existing antimalarial medications. The UV–Visible (UV–Vis) spectral properties of methanolic leaf extracts from five antimalarial medicinal plants Azadirachta indica, Momordica charantia, Spondias mombin, Mangifera indica, and Vernonia amygdalina were compared with those of a few common antimalarial medications, including quinine, chloroquine, and halofantrine Halfan. Methanol was used to extract fresh leaves that had been gathered from the Benin Forest, air dried, and ground into a powder. The extracts and reference medications UV-Vis absorption spectra were recorded and their absorption maxima (λ_max) were examined and contrasted. In the UV spectrum, the plant extracts showed distinctive absorption peaks. Azadirachta indica (325 nm), Momordica charantia (418 nm), Spondias mombin (318 nm), Mangifera indica (345 nm), and Vernonia amygdalina (318 nm) were among the observed λ_max values. Standard medications displayed λ_max values at 319 nm (halofantrine), 418 nm and 346 nm (quinine), and 325 nm and 319 nm (chloroquine). A number of plant extracts showed absorption maxima in wavelength ranges that were equivalent to those of conventional antimalarial medications, indicating the existence of conjugated structures or similar chromophoric systems. The discovered spectrum similarities suggest possible phytochemical characteristics that might call for additional research utilising sophisticated analytical and biological assays, even though UV–Vis spectroscopy cannot give conclusive structural identification. These results lend credence to the ongoing investigation of traditional medicinal herbs as possible sources of bioactive chemicals with antimalarial properties.},
      keywords = {UV–Visible spectroscopy, antimalarial plants, phytochemical screening, methanolic extract, spectral comparison, medicinal plants.},
      month = {March},
      doi = {https://doi.org/10.64388/IREV9I9-1715347}
  }