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Optimized Multimodal Machine Learning Framework for Parkinson’s Disease Detection and Severity Analysis
Subject area: Science,Engineering and Technology · Area of research: Machine Learning
DOI: 10.64388/IREV9I10-1716254
Abstract
Parkinson’s disease is a chronic neurological disorder leading to subsequent deterioration of gait, speech and movement. Its early diagnosis is critically important as it can reduce the treatment costs and improve the patient's quality of life. Traditional diagnosis methods depend on clinical observations, which are subjective; hence, possible to overlook initial symptoms of the disease at its early stages. A machine learning based Parkinson’s disease early detection framework is presented in this project by taking a range of biomedical voice features: such as jitter, shimmer, pitch and harmonic-to-noise ratio as input parameters. Parkinson’s dataset from UCI is used for training the system, and the normalization and feature scaling techniques are implemented to enhance the system accuracy. Multiple machine learning algorithms, namely Logistic Regression, SVM, Random Forest classifier, have been compared with each other on the basis of various metrics such as accuracy, Precision, Recall, F1-score and confusion matrix. The results display that SVM and Random Forest Classifier perform well among others. We also deploy our trained framework to a user friendly implementation via a simple web interface for facilitating early diagnosis of the disease using a low-cost, non-invasive and efficient system to benefit the practitioner and the decision maker.
Keywords
Parkinson’s Disease Detection, Voice Analysis, Gait Analysis, Multimodal Learning, Optimization Algorithms
References
[1] S. Arora, J. Venkataraman, S. Zhan, S. Donohue, K. Biglan, and M. Little, “Detecting and monitoring the symptoms of Parkinson’s disease using smartphones: A pilot study,” Parkinsonism & Related Disorders, vol. 21, no. 6, pp. 650–653, 2015.
[2] M. A. Little, P. E. McSharry, E. J. Hunter, J. Spielman, and L. O. Ramig, “Suitability of dysphonia measurements for telemonitoring of Parkinson’s disease,” IEEE Transactions on Biomedical Engineering, vol. 56, no. 4, pp. 1015–1022, 2009.
[3] J. S. Perlmutter and J. W. Mink, “Deep brain stimulation,” Annual Review of Neuroscience, vol. 29, pp. 229–257, 2006.
[4] J. Postuma et al., “MDS clinical diagnostic criteria for Parkinson’s disease,” Movement Disorders, vol. 30, no. 12, pp. 1591–1601, 2015.
[5] U. R. Acharya, S. V. Sree, G. Swapna, R. J. Martis, and J. S. Suri, “Automated diagnosis of Parkinson’s disease using biomedical voice measurements,” Computers in Biology and Medicine, vol. 64, pp. 1–10, 2015.
[6] S. M. Prashanth, P. K. Dutta, S. Mandal, and N. B. Puhan, “High-accuracy classification of Parkinson’s disease through shape analysis and surface fitting in 3D handwriting data,” IEEE Journal of Biomedical and Health Informatics, vol. 21, no. 2, pp. 568–576, 2017.
[7] L. Breiman, “Random forests,” Machine Learning, vol. 45, no. 1, pp. 5–32, 2001.
[8] T. Chen and C. Guestrin, “XGBoost: A scalable tree boosting system,” in Proc. 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, 2016, pp. 785–794.
[9] S. Hochreiter and J. Schmidhuber, “Long short-term memory,” Neural Computation, vol. 9, no. 8, pp. 1735–1780, 1997.
[10] D. Gil and M. Johnson, “Speech signal processing for Parkinson’s disease detection,” Biomedical Signal Processing and Control, vol. 8, no. 6, pp. 601–608, 2013.
[11] M. Nilashi, O. Ibrahim, H. Ahmadi, and L. Shahmoradi, “A knowledge-based system for Parkinson’s disease detection using machine learning techniques,” Journal of Medical Systems, vol. 41, no. 10, pp. 1–13, 2017.
[12] H. Eskofier et al., “Recent machine learning advancements in sensor-based mobility analysis: Deep learning for Parkinson’s disease assessment,” IEEE Reviews in Biomedical Engineering, vol. 10, pp. 1–15, 2017.
[13] A. Tsanas, M. Little, P. McSharry, and L. Ramig, “Accurate telemonitoring of Parkinson’s disease progression by non-invasive speech tests,” IEEE Transactions on Biomedical Engineering, vol. 57, no. 4, pp. 884–893, 2010.
[14] J. M. Hausdorff, “Gait dynamics in Parkinson’s disease: Common and distinct behavior among stride length, gait variability, and fractal-like scaling,” Chaos, vol. 19, no. 2, 2009.
[15] A. H. S. Soliman and M. M. Hassanien, “Deep learning approaches for Parkinson’s disease detection using biomedical signals,” IEEE Access, vol. 8, pp. 131-140, 2020.
[16] A. Tsanas, M. A. Little, P. E. McSharry, and L. O. Ramig, “Nonlinear speech analysis algorithms mapped to a standard metric achieve clinically useful quantification of average Parkinson’s disease symptom severity,” Journal of the Royal Society Interface, vol. 8, no. 59, pp. 842–855, 2011.
[17] J. Cancela, M. Pastorino, M. Tzallas, M. Tsipouras, and D. Fotiadis, “Wearability assessment of a wearable system for Parkinson’s disease remote monitoring based on a body area network of sensors,” Sensors, vol. 14, no. 9, pp. 17235–17255, 2014.
[18] Mengshoel, J. Zhu, P. Wu, and J. Zhang, “Convolutional neural networks for human activity recognition using mobile sensors,” in Proc. 6th International Conference on Mobile Computing, Applications and Services, 2014, pp. 197–205.
[19] H. Gunduz, “Deep learning-based Parkinson’s disease classification using vocal feature sets,” IEEE Access, vol. 7, pp. 115540–115551, 2019.
[20] S. Sakar et al., “A comparative analysis of speech signal processing algorithms for Parkinson’s disease classification and the use of the UCI machine learning repository dataset,” Biomedical Signal Processing and Control, vol. 13, pp. 52–60, 2014.
How to cite this paper
@article{1716254,
author = {Dr. P. S. Smitha, Anbumani J, Surya K, Vishal B},
title = {Optimized Multimodal Machine Learning Framework for Parkinson’s Disease Detection and Severity Analysis},
journal = {Iconic Research And Engineering Journals},
year = {2026},
volume = {9},
number = {10},
pages = {1352-1362},
issn = {2456-8880},
url = {https://www.irejournals.com/formatedpaper/1716254.pdf},
abstract = {Parkinson’s disease is a chronic neurological disorder leading to subsequent deterioration of gait, speech and movement. Its early diagnosis is critically important as it can reduce the treatment costs and improve the patient's quality of life. Traditional diagnosis methods depend on clinical observations, which are subjective; hence, possible to overlook initial symptoms of the disease at its early stages. A machine learning based Parkinson’s disease early detection framework is presented in this project by taking a range of biomedical voice features: such as jitter, shimmer, pitch and harmonic-to-noise ratio as input parameters. Parkinson’s dataset from UCI is used for training the system, and the normalization and feature scaling techniques are implemented to enhance the system accuracy. Multiple machine learning algorithms, namely Logistic Regression, SVM, Random Forest classifier, have been compared with each other on the basis of various metrics such as accuracy, Precision, Recall, F1-score and confusion matrix. The results display that SVM and Random Forest Classifier perform well among others. We also deploy our trained framework to a user friendly implementation via a simple web interface for facilitating early diagnosis of the disease using a low-cost, non-invasive and efficient system to benefit the practitioner and the decision maker.},
keywords = {Parkinson’s Disease Detection, Voice Analysis, Gait Analysis, Multimodal Learning, Optimization Algorithms},
month = {April},
doi = {https://doi.org/10.64388/IREV9I10-1716254}
}