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1717227 Vol 9 · Issue 11 Download Paper

Malaria Detection Using an Improved AlexNet-Based Deep Learning Model

M. Phanindra K. Venkata Siva Sai Sreeja P. Nikhil

Subject area: Science,Engineering and Technology  ·  Area of research: Artificial Intelligence / Machine Learning

DOI: https://doi.org/10.64388/IREV9I11-1717227

Abstract

Diagnosing malaria still relies heavily on microscope examination of blood smears — which works, but is slow, hard to scale, and only as good as the person doing it. This paper describes a deep learning pipeline for binary malaria cell screening built on a modified AlexNet CNN. We used the public NIH/Kaggle malaria cell-image dataset, resized everything to 100×100 RGB patches, applied live augmentation, and trained a regularized CNN with batch normalization and dropout. Beyond just reporting accuracy, we evaluated the model with confusion matrices, ROC-AUC, precision-recall curves, calibration plots, and Grad-CAM heatmaps. We also compare the approach against a recent two-stage YOLOv4/DenseNet-121 system. This model doesn't do whole-slide detection or species identification — it's a clean, reproducible infected-vs-uninfected screener that can be understood, explained, and built on.

Keywords

Malaria Detection, Alexnet, Convolutional Neural Network, Grad-CAM, Medical Image Classification, Binary Screening.

References

[1] D. Sukumarran et al., "Automated Identification of Malaria-Infected Cells and Classification of Human Malaria Parasites Using a Two-Stage Deep Learning Technique," IEEE Access, vol. 12, 2024.

[2] A. Krizhevsky, I. Sutskever, and G. E. Hinton, "ImageNet Classification with Deep Convolutional Neural Networks," NeurIPS, 2012.

[3] G. Huang et al., "Densely Connected Convolutional Networks," CVPR, 2017.

[4] R. R. Selvaraju et al., "Grad-CAM: Visual Explanations from Deep Networks via Gradient-Based Localization," ICCV, 2017.

[5] I. Arunava, "Cell Images for Detecting Malaria," Kaggle Dataset.

[6] S. Rajaraman et al., "Pre-trained convolutional neural networks as feature extractors toward improved malaria parasite detection," PeerJ, 2018.

How to cite this paper

M. Phanindra, K. Venkata Siva Sai Sreeja, P. Nikhil "Malaria Detection Using an Improved AlexNet-Based Deep Learning Model" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 472-474 https://doi.org/10.64388/IREV9I11-1717227
M. Phanindra, K. Venkata Siva Sai Sreeja, P. Nikhil "Malaria Detection Using an Improved AlexNet-Based Deep Learning Model" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026, doi: https://doi.org/10.64388/IREV9I11-1717227
M. Phanindra, K. Venkata Siva Sai Sreeja, P. Nikhil (2026). Malaria Detection Using an Improved AlexNet-Based Deep Learning Model. Iconic Research And Engineering Journals, 9(11). doi: https://doi.org/10.64388/IREV9I11-1717227
M. Phanindra, K. Venkata Siva Sai Sreeja, P. Nikhil "Malaria Detection Using an Improved AlexNet-Based Deep Learning Model" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026. Crossref, https://doi.org/10.64388/IREV9I11-1717227
@article{1717227,
      author = {M. Phanindra, K. Venkata Siva Sai Sreeja, P. Nikhil},
      title = {Malaria Detection Using an Improved AlexNet-Based Deep Learning Model},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {11},
      pages = {472-474},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1717227.pdf},
      abstract = {Diagnosing malaria still relies heavily on microscope examination of blood smears — which works, but is slow, hard to scale, and only as good as the person doing it. This paper describes a deep learning pipeline for binary malaria cell screening built on a modified AlexNet CNN. We used the public NIH/Kaggle malaria cell-image dataset, resized everything to 100×100 RGB patches, applied live augmentation, and trained a regularized CNN with batch normalization and dropout. Beyond just reporting accuracy, we evaluated the model with confusion matrices, ROC-AUC, precision-recall curves, calibration plots, and Grad-CAM heatmaps. We also compare the approach against a recent two-stage YOLOv4/DenseNet-121 system. This model doesn't do whole-slide detection or species identification — it's a clean, reproducible infected-vs-uninfected screener that can be understood, explained, and built on.},
      keywords = {Malaria Detection, Alexnet, Convolutional Neural Network, Grad-CAM, Medical Image Classification, Binary Screening.},
      month = {May},
      doi = {https://doi.org/10.64388/IREV9I11-1717227}
  }