International Peer-Reviewed JournalOpen AccessISSN 2456-8880
irejournals@gmail.com+91-7433024337

Home / Current Issue / Paper 1717501

1717501PublishedVol 9 · Issue 11

Early Detection of Alzheimer’s Disease Using Machine Learning

Om Patkar Vedant Khorjekar Rhitikesh Gaikwad Prof. Salabha Jacob

Subject area: Science,Engineering and Technology  ·  Area of research: Engineering

DOI: https://doi.org/10.64388/IREV9I11-1717501

Abstract

Early detection of Alzheimer’s disease (AD) is critical for timely intervention and slowing disease progression. Manual analysis of MRI scans is labor-intensive and subject to inter-clinician variability. This paper presents an end-to-end deep learning system for automated classification of Alzheimer’s stages using brain MRI images. A Convolutional Neural Network (CNN) is trained to classify images into four categories: Non-Demented, Very Mild Demented, Mild Demented, and Moderate Demented, achieving a test accuracy of 99.84% on 1,276 held-out samples from the Kaggle Alzheimer MRI Dataset (6,376 images total). The system is deployed via a Streamlit web interface for real-time prediction, enhanced with Grad-CAM visualization to highlight discriminative brain regions. Batch processing and timestamped prediction history tracking are also supported. Experimental results demonstrate sub-second inference latency, confirming the system’s potential as a clinical decision-support tool.

Keywords

Alzheimer’s Disease, CNN, Deep Learning, Grad-CAM, MRI, Streamlit

How to cite this paper

Om Patkar, Vedant Khorjekar, Rhitikesh Gaikwad, Prof. Salabha Jacob "Early Detection of Alzheimer’s Disease Using Machine Learning" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 1486-1489 https://doi.org/10.64388/IREV9I11-1717501
Om Patkar, Vedant Khorjekar, Rhitikesh Gaikwad, Prof. Salabha Jacob "Early Detection of Alzheimer’s Disease Using Machine Learning" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026, doi: https://doi.org/10.64388/IREV9I11-1717501
Om Patkar, Vedant Khorjekar, Rhitikesh Gaikwad, Prof. Salabha Jacob (2026). Early Detection of Alzheimer’s Disease Using Machine Learning. Iconic Research And Engineering Journals, 9(11). doi: https://doi.org/10.64388/IREV9I11-1717501
Om Patkar, Vedant Khorjekar, Rhitikesh Gaikwad, Prof. Salabha Jacob "Early Detection of Alzheimer’s Disease Using Machine Learning" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026. Crossref, https://doi.org/10.64388/IREV9I11-1717501
@article{1717501,
      author = {Om Patkar, Vedant Khorjekar, Rhitikesh Gaikwad, Prof. Salabha Jacob},
      title = {Early Detection of Alzheimer’s Disease Using Machine Learning},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {11},
      pages = {1486-1489},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1717501.pdf},
      abstract = {Early detection of Alzheimer’s disease (AD) is critical for timely intervention and slowing disease progression. Manual analysis of MRI scans is labor-intensive and subject to inter-clinician variability. This paper presents an end-to-end deep learning system for automated classification of Alzheimer’s stages using brain MRI images. A Convolutional Neural Network (CNN) is trained to classify images into four categories: Non-Demented, Very Mild Demented, Mild Demented, and Moderate Demented, achieving a test accuracy of 99.84% on 1,276 held-out samples from the Kaggle Alzheimer MRI Dataset (6,376 images total). The system is deployed via a Streamlit web interface for real-time prediction, enhanced with Grad-CAM visualization to highlight discriminative brain regions. Batch processing and timestamped prediction history tracking are also supported. Experimental results demonstrate sub-second inference latency, confirming the system’s potential as a clinical decision-support tool.},
      keywords = {Alzheimer’s Disease, CNN, Deep Learning, Grad-CAM, MRI, Streamlit},
      month = {May},
      doi = {https://doi.org/10.64388/IREV9I11-1717501}
  }