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1717648 Vol 9 · Issue 11 Download Paper

Intelligent Rare Medical Event Detection

Soham Mhatre Dr. Pratibha Adkar

Subject area: Science,Engineering and Technology  ·  Area of research: Medical AI

DOI: https://doi.org/10.64388/IREV9I11-1717648

Abstract

Identifying rare diseases is one of the toughest hurdles in modern medicine be-cause information is scarce and symptoms are often confusingly diverse, which fre-quently leads to long and stressful diag-nostic delays for patients. To solve this, we created CliniFlow AI, an intelligent platform designed to help doctors spot these rare conditions much earlier using a unique "brain" called Anomaly-Aware Adaptive Multimodal Fusion (A²MF), al-lowing it to recognize over 230 rare dis-eases even when data is extremely lim-ited. The system connects the dots by ana-lyzing clinical text with BioBERT, spot-ting abnormalities in medical images with a customized ResNet-50, and tracking a patient's health history over time using LSTM networks. By flagging unusual pat-terns through Anomaly Detection and learning from a small number of examples via Few-Shot Learning, CliniFlow AI pro-vides doctors with clear risk levels and diagnostic insights, making it a powerful and easy-to-scale tool for real-world hos-pitals. Beyond simple automation, this framework acts as a second pair of eyes that stays sharp during high-stakes medi-cal screenings where every minute counts. It effectively bridges the gap between massive amounts of raw hospital data and the specialized, actionable knowledge cli-nicians need to save lives.

Keywords

Rare Disease Detection, Mul-timodal Learning, Clinical Decision Sup-port System, Medical Image Analysis, Bi-oBERT, Few-Shot Learning, Anomaly De-tection, Explainable AI.

References

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[3] Abdulrazaq, M. (2014). “Rare Event Prediction in Highly Imbal-ancedDatasets.” International Journal of Data Mining and Knowledge Discovery, Vol. 8, No. 4, pp. 245–255.

[4] Alshemaimri, B., Daud, A., & Kha-lique, F.(2015). “Anomaly Detection in Smart Healthcare Systems Using Isolation Forest and Local OutlierFactor.” International Journal of Information Secu-rity and Applications, Vol. 21, pp. 75–84.

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[7] Luo, Y., Fu, Y., & Wang, F. (2019). “Machine Learning Approaches for Rare Disease Detection in Longitudinal Healthcare Data.” IEEE Journal of Biomedical and Health Informatics, Vol. 23, No. 4, pp. 1450–1460.

[8] Yang, C., Wang, T., & Jiang, X. (2020) “Deep Autoencoder-Based Anomaly De-tectionfor Healthcare Data.” IEEE Access, Vol. 8, pp. 108–117.

[9] Niu, H., & Omitaomu, O. A. (2020). “EHR-BERT: A Transformer-Based Model for Electronic Health Record Analysis.” IEEE International Conference on Healthcare Informatics, pp. 120–128.

[10] Xun, G., Ma, F., Gao, J., & Zhang, A. (2021). “Graph-Based Deep Learning for Rare Disease Detection in Electronic Health Records.” ACM Transactions on Knowledge Discov-ery from Data, Vol. 15, No. 3, pp. 1–22.

[11] Shukla, P. K., Shukla, P., & Pandey, A.(2022). “Multimodal Transformer Framework for Rare Disease Diagnosis.” IEEE Access, Vol. 10, pp. 45678–45689.

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How to cite this paper

Soham Mhatre, Dr. Pratibha Adkar "Intelligent Rare Medical Event Detection" Iconic Research And Engineering Journals Volume 9 Issue 11 2026 Page 1479-1485 https://doi.org/10.64388/IREV9I11-1717648
Soham Mhatre, Dr. Pratibha Adkar "Intelligent Rare Medical Event Detection" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026, doi: https://doi.org/10.64388/IREV9I11-1717648
Soham Mhatre, Dr. Pratibha Adkar (2026). Intelligent Rare Medical Event Detection. Iconic Research And Engineering Journals, 9(11). doi: https://doi.org/10.64388/IREV9I11-1717648
Soham Mhatre, Dr. Pratibha Adkar "Intelligent Rare Medical Event Detection" Iconic Research And Engineering Journals, vol. 9, no. 11, May. 2026. Crossref, https://doi.org/10.64388/IREV9I11-1717648
@article{1717648,
      author = {Soham Mhatre, Dr. Pratibha Adkar},
      title = {Intelligent Rare Medical Event Detection},
      journal = {Iconic Research And Engineering Journals},
      year = {2026},
      volume = {9},
      number = {11},
      pages = {1479-1485},
      issn = {2456-8880},
      url = {https://www.irejournals.com/formatedpaper/1717648.pdf},
      abstract = {Identifying rare diseases is one of the toughest hurdles in modern medicine be-cause information is scarce and symptoms are often confusingly diverse, which fre-quently leads to long and stressful diag-nostic delays for patients. To solve this, we created CliniFlow AI, an intelligent platform designed to help doctors spot these rare conditions much earlier using a unique "brain" called Anomaly-Aware Adaptive Multimodal Fusion (A²MF), al-lowing it to recognize over 230 rare dis-eases even when data is extremely lim-ited. The system connects the dots by ana-lyzing clinical text with BioBERT, spot-ting abnormalities in medical images with a customized ResNet-50, and tracking a patient's health history over time using LSTM networks. By flagging unusual pat-terns through Anomaly Detection and learning from a small number of examples via Few-Shot Learning, CliniFlow AI pro-vides doctors with clear risk levels and diagnostic insights, making it a powerful and easy-to-scale tool for real-world hos-pitals. Beyond simple automation, this framework acts as a second pair of eyes that stays sharp during high-stakes medi-cal screenings where every minute counts. It effectively bridges the gap between massive amounts of raw hospital data and the specialized, actionable knowledge cli-nicians need to save lives.},
      keywords = {Rare Disease Detection, Mul-timodal Learning, Clinical Decision Sup-port System, Medical Image Analysis, Bi-oBERT, Few-Shot Learning, Anomaly De-tection, Explainable AI.},
      month = {May},
      doi = {https://doi.org/10.64388/IREV9I11-1717648}
  }